Catalog No.
PHJ86501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human AXIN2 (Pro350-Lys631).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Axin-like protein, AXIN2, Axin-2, Axis inhibition protein 2, Axil, Conductin
Purification
Purified by antigen affinity column.
Accession
Q9Y2T1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Over-expressed Phospholamban in Cancer-associated Fibroblasts Is a Driver for CMS4 Subtype Colorectal Cancer Formation., PMID:40288441
Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259
Sclerostin blockade promotes bone metastases of Wnt-responsive breast cancer cells., PMID:36840409
Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo., PMID:34854998
Ibrutinib With Rituximab in First-Line Treatment of Older Patients With Mantle Cell Lymphoma., PMID:34797699
Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation., PMID:33493531
Inhibition of Wnt signaling by Frizzled7 antibody-coated nanoshells sensitizes triple-negative breast cancer cells to the autophagy regulator chloroquine., PMID:33304449
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer., PMID:32972302
Liuwei Dihuang pill suppresses metastasis by regulating the wnt pathway and disrupting -catenin/T cell factor interactions in a murine model of triple-negative breast cancer., PMID:32186153
Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus., PMID:30651970
FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2., PMID:29718273
Mesenchymal Wnt/β-catenin signaling limits tooth number., PMID:29437780
Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice., PMID:29059455
A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma., PMID:28892521
Frizzled7 Antibody-Functionalized Nanoshells Enable Multivalent Binding for Wnt Signaling Inhibition in Triple Negative Breast Cancer Cells., PMID:28544579
The influence of tumor necrosis factor-α on the tumorigenic Wnt-signaling pathway in human mammary tissue from obese women., PMID:28402277
Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts., PMID:27264700
Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model., PMID:27207671
Tissue inhibitor of metalloproteinase 2 inhibits activation of the β-catenin signaling in melanoma cells., PMID:25839957
Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors., PMID:25401739
CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling., PMID:25356755
The increase in maternal expression of axin1 and axin2 contribute to the zebrafish mutant ichabod ventralized phenotype., PMID:25335865
Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/β-catenin signaling pathway., PMID:25305448
Aberrant activation of the WNT/β-catenin signaling pathway in lupus nephritis., PMID:24465439
Secreted Frizzled-related protein 2 as a target in antifibrotic therapeutic intervention., PMID:24336656
Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells., PMID:24188694
Differential expression of Wnt signaling molecules between pre- and postmenopausal endometrial epithelial cells suggests a population of putative epithelial stem/progenitor cells reside in the basalis layer., PMID:22474188
Inhibition of melanogenesis by the pyridinyl imidazole class of compounds: possible involvement of the Wnt/β-catenin signaling pathway., PMID:22427932
Aberrant chondrocyte hypertrophy and activation of β-catenin signaling precede joint ankylosis in ank/ank mice., PMID:22298904
Coordination of epithelial branching and salivary gland lumen formation by Wnt and FGF signals., PMID:21806977
Active Wnt signaling in response to cardiac injury., PMID:20373104
Axin localizes to mitotic spindles and centrosomes in mitotic cells., PMID:19331826
Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina., PMID:18599572
Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma., PMID:18384130
Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas., PMID:18084253
Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments., PMID:17895986
WNT signaling pathway and stem cell signaling network., PMID:17634527
Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner., PMID:17189293
Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention., PMID:16554443
Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer., PMID:16273202
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations., PMID:15735684
Alterations of beta-catenin pathway in non-melanoma skin tumors: loss of alpha-ABC nuclear reactivity correlates with the presence of beta-catenin gene mutation., PMID:14633602
For research use only. Not for human or drug use.
