Catalog No.
PHE41501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NR4A2 (Met1-Thr335).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Transcriptionally-inducible nuclear receptor, NURR1, NR4A2, NOT, Nuclear receptor subfamily 4 group A member 2, Orphan nuclear receptor NURR1, TINUR, Immediate-early response protein NOT
Purification
Purified by antigen affinity column.
Accession
P43354
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transcriptomic analysis of chronic chikungunya in the Reunionese CHIKGene cohort uncovers a shift in gene expression more than 10 years after infection., PMID:39999933
Tertiary Lymphoid Structures are Linked to Enhanced Antitumor Immunity and Better Prognosis in Muscle-Invasive Bladder Cancer., PMID:39739621
The Promotion of Humoral Immune Responses in Humans via SOCS1-Mediated Th2-Bias Following SARS-CoV-2 Vaccination., PMID:38006062
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy., PMID:39872303
A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors., PMID:36469101
Systematic characterization of the tumor microenvironment in Chinese patients with hepatocellular carcinoma highlights intratumoral B cells as a potential immunotherapy target., PMID:34958112
The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma., PMID:34076685
Evaluation of changes in expression pattern of oxidative stress genes under the influence of adalimumab., PMID:31664747
Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation., PMID:31301888
Low-dose ionizing radiation attenuates mast cell migration through suppression of monocyte chemoattractant protein-1 (MCP-1) expression by Nr4a2., PMID:31287373
Pyrethroid exposure and neurotoxicity: a mechanistic approach., PMID:31246571
Sequential cleavage of the proteins encoded by HNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, results in products acting in distinct cellular compartments., PMID:30192950
cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjögren's syndrome., PMID:28621822
Chiro-Optical Modulation for NURR1 Production from Stem Cells., PMID:28452458
Nurr1 overexpression exerts neuroprotective and anti-inflammatory roles via down-regulating CCL2 expression in both in vivo and in vitro Parkinson's disease models., PMID:27940361
Production of Nurr-1 Specific Polyclonal Antibodies Free of Cross-reactivity Against Its Close Homologs, Nor1 and Nur77., PMID:26325389
Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy., PMID:26096603
Nuclear receptors of the NR4a family are not required for the development and function of follicular T helper cells., PMID:25899083
Chronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity., PMID:25855987
A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure., PMID:25658712
Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease., PMID:25156412
Layer-specific gene expression in epileptogenic type II focal cortical dysplasia: normal-looking neurons reveal the presence of a hidden laminar organization., PMID:24735483
Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation., PMID:24496614
High-dimensional gene expression profiling studies in high and low responders to primary smallpox vaccination., PMID:22949304
Molecular diversity of early-born subplate neurons., PMID:22628460
Transplantation of neuronal-primed human bone marrow mesenchymal stem cells in hemiparkinsonian rodents., PMID:21625433
Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation., PMID:21621845
Transgenic mice as a model of pre-clinical Alzheimer's disease., PMID:21143159
Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer., PMID:20010869
Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development., PMID:19906978
Identification of a novel nurr1-interacting protein., PMID:18784308
Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis., PMID:18252802
Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition., PMID:17671512
A role for type 1alpha corticotropin-releasing hormone receptors in mediating local changes in chronically inflamed tissue., PMID:17322394
Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death., PMID:16805795
Efficient generation of dopaminergic neurons from mouse embryonic stem cells enclosed in hollow fibers., PMID:16766027
Tyrosine hydroxylase gene regulation in human neuronal progenitor cells does not depend on Nurr1 as in the murine and rat systems., PMID:16252282
Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion., PMID:16243537
Nuclear orphan receptor Nurr1 directly transactivates the osteocalcin gene in osteoblasts., PMID:15485875
Modulation of nurr1 gene expression in mesencephalic dopaminergic neurones., PMID:15009684
Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice., PMID:14742729
Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra., PMID:12209851
[INFLUENCE OF PH AND SALT CONCENTRATION ON THE SOLUBILITY OF HUMAN SERUM PROTEINS IN O.O1 N PHYTIC ACID]., PMID:14278850
[ENDOTOXIN AS AN ADJUVANT. I. EFFECT ON THE LEVEL OF PRECIPITINS AGAINST HUMAN SERUM PROTEINS]., PMID:14203988
Immunoelectrophoretic analysis of rabbit precipitins against human serum proteins. I. Homologous reaction., PMID:13972398
Immunoelectrophoretic analysis of rabbit precipitins against human serum proteins. II. Heterologous reaction., PMID:13972397
Immunochemical studies of human serum proteins. Antigenic inhomogeneities of the gamma globulins, their subunits and number of determinants and their relation to a Waldenstrom macroglobulin., PMID:13863260
For research use only. Not for human or drug use.
