Catalog No.
PHG14101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TNK2 (Leu126-Leu385).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ACK-1, ACK1, TNK2, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2
Purification
Purified by antigen affinity column.
Accession
Q07912
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer., PMID:24178904
Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation., PMID:22952966
Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity., PMID:20623637
Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases., PMID:20383201
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1., PMID:20110370
An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1., PMID:17592719
A subset of CD16-natural killer cells without antibody-dependent cellular cytotoxicity function., PMID:2141105
For research use only. Not for human or drug use.
