Catalog No.
PHJ99001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CLMP (Thr19-Ser183).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CLMP, ACAM, CAR-like membrane protein, Adipocyte adhesion molecule, CXADR-like membrane protein, Coxsackie- and adenovirus receptor-like membrane protein, ASAM
Purification
Purified by antigen affinity column.
Accession
Q9H6B4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis., PMID:36241608
JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy., PMID:34427588
Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis., PMID:34127684
Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum., PMID:28381574
A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo., PMID:28074864
Cell-cell communication mediated by the CAR subgroup of immunoglobulin cell adhesion molecules in health and disease., PMID:27871939
Coxsackievirus and Adenovirus Receptor, a Tight Junction Protein, in Peri-Implantation Mouse Embryos., PMID:27226313
Redirecting adenoviruses to tumour cells using therapeutic antibodies: Generation of a versatile human bispecific adaptor., PMID:26391350
The IgCAMs CAR, BT-IgSF, and CLMP: structure, function, and diseases., PMID:25300131
Cytokines, polarity proteins, and endosomal protein trafficking and signaling-the sertoli cell blood-testis barrier system in vitro as a study model., PMID:24359954
Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeys., PMID:22787208
Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice., PMID:22624044
Efficient antitumor effects of carrier cells loaded with a fiber-substituted conditionally replicating adenovirus on CAR-negative tumor cells., PMID:22076042
Use of Cre/loxP recombination to swap cell binding motifs on the adenoviral capsid protein IX., PMID:21968200
Human platelets express CAR with localization at the sites of intercellular interaction., PMID:21962080
The transduction of Coxsackie and Adenovirus Receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus., PMID:21959008
Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells., PMID:21949793
Drifting motions of the adenovirus receptor CAR and immobile integrins initiate virus uncoating and membrane lytic protein exposure., PMID:21843868
Gene therapy with recombinant adenovirus encoding endostatin encapsulated in cationic liposome in coxsackievirus and adenovirus receptor-deficient colon carcinoma murine models., PMID:21615297
Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA., PMID:21531456
Novel splice variant CAR 4/6 of the coxsackie adenovirus receptor is differentially expressed in cervical carcinogenesis., PMID:21431326
Coxsackie and adenovirus receptor is a target and a mediator of estrogen action in breast cancer., PMID:21389059
Molecular insights into γδ T cell costimulation by an anti-JAML antibody., PMID:21220118
Tight junctions in cancer metastasis., PMID:21196209
Construction of metabolically biotinylated adenovirus with deleted fiber knob as targeting vector., PMID:21073735
Antibody-dependent enhancement of coxsackievirus B3 infection of primary CD19+ B lymphocytes., PMID:20712481
The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells., PMID:20181587
Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation., PMID:20110422
Suppression of ovarian cancer growth via systemic administration with liposome-encapsulated adenovirus-encoding endostatin., PMID:19609295
Adenovirus-mediated thymidine kinase gene therapy and coxsackie adenovirus receptor expression in ovarian cancer cells., PMID:19287072
ERK MAP kinase-activated Arf6 trafficking directs coxsackievirus type B3 into an unproductive compartment during virus host-cell entry., PMID:19264606
Replication-competent Ad11p vector (RCAd11p) efficiently transduces and replicates in hormone-refractory metastatic prostate cancer cells., PMID:19199789
Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors., PMID:19147569
Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression., PMID:19142187
Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1., PMID:19131551
Complement component C1q and anti-hexon antibody mediate adenovirus infection of a CAR-negative cell line., PMID:19115936
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart., PMID:18636119
Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: not insurmountable therapeutic problems., PMID:18277093
Primary neurons become less susceptible to coxsackievirus B5 following maturation: the correlation with the decreased level of CAR expression on cell surface., PMID:18205224
An oncolytic adenovirus redirected with a tumor-specific T-cell receptor., PMID:18056457
Adenovirus vectors composed of subgroup B adenoviruses., PMID:17969556
Endogenous low-level expression of the coxsackievirus and adenovirus receptor enables coxsackievirus B3 infection of RD cells., PMID:17947527
Treatment of metastatic renal cancer with capsid-modified oncolytic adenoviruses., PMID:17938266
Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the Kruppel family proteins, KLF4 and Sp1, in mouse TM4 Sertoli cells., PMID:17620326
[Role of a novel protein, CAR-like soluble protein (CLSP), in adenovirus infection]., PMID:17603268
Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter., PMID:17545616
Solution structure of the coxsackievirus and adenovirus receptor domain 2., PMID:17322536
Adenoviral receptor expression of normal bladder and transitional cell carcinoma of the bladder., PMID:17293658
Coxsackievirus and adenovirus receptor expression in non-malignant lung tissues and clinical lung cancers., PMID:17031523
Adenovirus fiber shaft contains a trimerization element that supports peptide fusion for targeted gene delivery., PMID:17020947