Catalog No.
PHJ74501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TJP2 (Gly307-Ala669).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TJP2, ZO2, Zonula occludens protein 2, Tight junction protein ZO-2, Tight junction protein 2, X104, Zona occludens protein 2
Purification
Purified by antigen affinity column.
Accession
Q9UDY2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Novel Compound Heterozygous Mutation in Progressive Familial Intrahepatic Cholestasis (PFIC) 4: A Rare Case Report With Literature Review., PMID:39697951
Clinical outcomes of surgical management for rare types of progressive familial intrahepatic cholestasis: a case series., PMID:35024979
Targeting tumor lineage plasticity in hepatocellular carcinoma using an anti-CLDN6 antibody-drug conjugate., PMID:33536280
Progressive familial intrahepatic cholestasis type 4 in an Indian child: presentation, initial course and novel compound heterozygous mutation., PMID:32636225
HAVcR-1 reduces the integrity of human endothelial tight junctions., PMID:21378325
Role of claudin species-specific dynamics in reconstitution and remodeling of the zonula occludens., PMID:21372174
Fibrinogen induces alterations of endothelial cell tight junction proteins., PMID:19507189
The tight junction protein ZO-2 mediates proliferation of vascular smooth muscle cells via regulation of Stat1., PMID:19380416
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane., PMID:19299464
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells., PMID:18353970
Molecular mechanisms underlying the probiotic effects of Escherichia coli Nissle 1917 involve ZO-2 and PKCzeta redistribution resulting in tight junction and epithelial barrier repair., PMID:17087734
Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina., PMID:16650609
Regulation of cellular and molecular trafficking across human brain endothelial cells by Th1- and Th2-polarized lymphocytes., PMID:15055446
Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues., PMID:14622136
[LIM protein KyoT2 interacts with human tight junction protein ZO-2-i3]., PMID:12645256
Corneal epithelial tight junctions and their response to lipopolysaccharide challenge., PMID:11095601
Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1beta in primary human fetal astrocytes., PMID:11090614
Characterization of JOK-1, a human gastric epithelial cell line., PMID:10852347
Entamoeba histolytica disturbs the tight junction complex in human enteric T84 cell layers., PMID:10834936
Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin., PMID:10026224
Protein-binding domains of the tight junction protein, ZO-2, are highly conserved between avian and mammalian species., PMID:9837755
Subcellular distribution of tight junction-associated proteins (occludin, ZO-1, ZO-2) in rodent skin., PMID:9620290
Molecular environment of ZO-1 in epithelial and non-epithelial cells., PMID:7553918
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions., PMID:7798316
Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein., PMID:8132716
For research use only. Not for human or drug use.
