Catalog No.
PHA24501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CCS (Gln23-Gln269).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Copper chaperone for superoxide dismutase, CCS, Superoxide dismutase copper chaperone
Purification
Purified by antigen affinity column.
Accession
O14618
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Positive coactivator PC4 shows dynamic nucleolar distribution required for rDNA transcription and protein synthesis., PMID:40517275
Nanobodies and their derivatives: pioneering the future of cancer immunotherapy., PMID:40474230
The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis., PMID:40468327
Trem2 regulates microglial migratory responses via type I interferon signaling during photoreceptor degeneration., PMID:40468324
Expanding the Applicability of Cognitive Charts to the Entire Age Span., PMID:40309796
An intranasally administered IgM protects against antigenically distinct subtypes of influenza A viruses., PMID:40301359
ERK2-mediated phosphorylation of ZEB1 at S322 enhances PD-L1 expression and EMT, leading to pancreatic cancer progression., PMID:40296122
[Morphological and functional changes of secondary macular neovascularization in central serous chorioretinopathy under anti-VEGF treatment]., PMID:40199756
Real-life effectiveness of rituximab in different subsets of idiopathic inflammatory myopathies., PMID:40191951
An institutional COVID-19 initiative: creation of a biobank and serological data analysis in pre- and post-vaccination cohorts., PMID:40136202
BDNF secreted by mesenchymal stem cells improves aged oocyte quality and development potential by activating the ERK1/2 pathway., PMID:40122822
MDA5 protein mediating persistent ER stress/unfolded protein response contributes to endothelial-mesenchymal-transition of lung microvascular endothelial cell in dermatomyositis., PMID:40122798
Inclusion of ΑVβ3 integrin into extracellular vesicles in a caveolin-1 tyrosine-14- phosphorylation dependent manner and subsequent transfer to recipient melanoma cells promotes migration, invasion and metastasis., PMID:40098186
Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model., PMID:40087780
Association between pre-existing chronic conditions and severity of first SARS-CoV-2 infection symptoms among adults living in Canada: a population-based survey analysis from January 2020 to August 2022., PMID:40075342
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling., PMID:40011876
Atypical Hemolytic Uremic Syndrome Associated with BNT162b2 mRNA COVID-19 Vaccine in a Kidney Transplant Recipient: A Case Report and Literature Review., PMID:39997466
NK cell immunopotentiators-loaded nanoliposomes enhance ADCC effect for targeted therapy against HER2-positive breast cancer., PMID:39987140
The interplay of cancer-associated fibroblasts and apoptotic cancer cells suppresses lung cancer cell growth through WISP-1-integrin ανβ3-STAT1 signaling pathway., PMID:39966869
IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression., PMID:39962487
Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models., PMID:39898046
Role of the androgen receptor in melanoma aggressiveness., PMID:39837817
Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization., PMID:39810210
Multiple Myeloma in Italy: An Epidemiological Model by Treatment Line and Refractoriness Status., PMID:39809661
Updated Review for Guidelines for Cervical Cancer Screening in Immunosuppressed Women Without HIV Infection., PMID:39804372
A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories., PMID:39772242
NIR II Laser-Triggered Photothermal Nanoplatform for Multimodal Imaging-Guided Synergistic Therapy toward Colon Cancer., PMID:39747817
MDSC: a new potential breakthrough in CAR-T therapy for solid tumors., PMID:39702149
Correction: A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model., PMID:39668347
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model., PMID:39639332
Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression., PMID:39639312
Staphylococcus aureus enterotoxin sensitization is associated with declined capsaicin cough sensitivity in chronic obstructive pulmonary disease., PMID:39609584
Relationship between high-resolution computed tomography quantitative imaging analysis and physiological and clinical features in antisynthetase syndrome-related interstitial lung disease., PMID:39608864
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways., PMID:39533382
Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity., PMID:39516877
Randomized Phase II Study of Durvalumab with or without Tremelimumab in Patients with Metastatic Castration-Resistant Prostate Cancer., PMID:39513948
Serum levels of free light chains and syndecan-1 in patients with rheumatoid arthritis and systemic lupus erythematosus., PMID:39509329
Benzo (A) pyrene exposure alters alveolar epithelial and macrophage cells diversity and induces antioxidant responses in lungs., PMID:39506978
Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses., PMID:39488210
Long-term immunological changes after corrective cardiac surgery., PMID:39474990
Autoimmune Encephalitis and Paraneoplastic Neurologic Syndromes: A Nationwide Study on Epidemiology and Antibody Testing Performance., PMID:39467237
Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins., PMID:39461874
Immunomodulatory effects of trastuzumab deruxtecan through the cGAS-STING pathway in gastric cancer cells., PMID:39449023
Alternative splicing in ovarian cancer., PMID:39425166
Human mesenchymal stroma/stem-like cell-derived taxol-loaded EVs/exosomes transfer anti-tumor microRNA signatures and express enhanced SDF-1-mediated tumor tropism., PMID:39420354
Acetylcysteine synergizes PD-1 blockers against colorectal cancer progression by promoting TCF1+PD1+CD8+ T cell differentiation., PMID:39420342
Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes?, PMID:39394159
A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification., PMID:39383863
Case Report: Cronkhite-Canada syndrome: presentation of a pediatric case and review of the literature., PMID:39380635
In vivo edited eosinophils reconcile antigen specific Th2 response and mitigate airway allergy., PMID:39350231