Catalog No.
PHD47001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EPHA1 (Tyr599-Gly842).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Tyrosine-protein kinase receptor EPH, EPHT1, Erythropoietin-producing hepatoma receptor, hEpha1, EPH, EPHA1, Ephrin type-A receptor 1, EPH tyrosine kinase 1, EPH tyrosine kinase, EPHT
Purification
Purified by antigen affinity column.
Accession
P21709
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs., PMID:36806315
Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains., PMID:34508727
A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease., PMID:32296418
Inhibition of EphA/Ephrin-A signaling using genetic and pharmacologic approaches improves recovery following traumatic brain injury in mice., PMID:31319723
Serum biomarker panels for the diagnosis of gastric cancer., PMID:30873760
A potential role for Eph receptor signalling during migration of corneal endothelial cells., PMID:29476773
Glycoengineering of EphA4 Fc leads to a unique, long-acting and broad spectrum, Eph receptor therapeutic antagonist., PMID:28747680
EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells., PMID:28560458
Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab., PMID:26854735
Expression of the EphA1 protein is associated with Fuhrman nuclear grade in clear cell renal cell carcinomas., PMID:26261568
ADAM12-cleaved ephrin-A1 contributes to lung metastasis., PMID:23686306
Evaluation of Eph receptor and ephrin expression within the human cornea and limbus., PMID:23247085
The protection of acetylcholinesterase inhibitor on β-amyloid-induced the injury of neurite outgrowth via regulating axon guidance related genes expression in neuronal cells., PMID:23119107
Targeting of EPH receptor tyrosine kinases for anticancer therapy., PMID:22471709
Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System., PMID:22254144
Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis., PMID:21852108
EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines., PMID:21795402
Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2., PMID:21503576
Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice., PMID:21282286
[Neuronal identity and axonal projection of olfactory sensory neurons]., PMID:17552283
Comparison of EphA receptor tyrosine kinases and ephrinA ligand expression to EphB-ephrinB in vascularized corneas., PMID:17525654
Differential gene expression in non-malignant tumour microenvironment is associated with outcome in follicular lymphoma patients treated with rituximab and CHOP., PMID:16925574
Giant cell tumors of the bone: molecular profiling and expression analysis of Ephrin A1 receptor, Claudin 7, CD52, FGFR3 and AMFR., PMID:16325507
EphA receptor tyrosine kinases interact with co-expressed ephrin-A ligands in cis., PMID:15154674
Identification of tyrosine kinases overexpressed in head and neck cancer., PMID:15023838
Identification of NPM-ALK interacting proteins by tandem mass spectrometry., PMID:14968112
Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells., PMID:14707054
EphA4 provides repulsive signals to developing cochlear ganglion neurites mediated through ephrin-B2 and -B3., PMID:12761826
Topographic-specific axon branching controlled by ephrin-As is the critical event in retinotectal map development., PMID:11606643
Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner., PMID:11032807
PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization., PMID:10660600
For research use only. Not for human or drug use.
