Catalog No.
PHD47001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EPHA1 (Tyr599-Gly842).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Tyrosine-protein kinase receptor EPH, EPHT1, Erythropoietin-producing hepatoma receptor, hEpha1, EPH, EPHA1, Ephrin type-A receptor 1, EPH tyrosine kinase 1, EPH tyrosine kinase, EPHT
Purification
Purified by antigen affinity column.
Accession
P21709
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization., PMID:10660600
Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner., PMID:11032807
Topographic-specific axon branching controlled by ephrin-As is the critical event in retinotectal map development., PMID:11606643
EphA4 provides repulsive signals to developing cochlear ganglion neurites mediated through ephrin-B2 and -B3., PMID:12761826
Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells., PMID:14707054
Identification of NPM-ALK interacting proteins by tandem mass spectrometry., PMID:14968112
Identification of tyrosine kinases overexpressed in head and neck cancer., PMID:15023838
EphA receptor tyrosine kinases interact with co-expressed ephrin-A ligands in cis., PMID:15154674
Giant cell tumors of the bone: molecular profiling and expression analysis of Ephrin A1 receptor, Claudin 7, CD52, FGFR3 and AMFR., PMID:16325507
Differential gene expression in non-malignant tumour microenvironment is associated with outcome in follicular lymphoma patients treated with rituximab and CHOP., PMID:16925574
Comparison of EphA receptor tyrosine kinases and ephrinA ligand expression to EphB-ephrinB in vascularized corneas., PMID:17525654
[Neuronal identity and axonal projection of olfactory sensory neurons]., PMID:17552283
Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice., PMID:21282286
Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2., PMID:21503576
EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines., PMID:21795402
Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis., PMID:21852108
Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System., PMID:22254144
Targeting of EPH receptor tyrosine kinases for anticancer therapy., PMID:22471709
The protection of acetylcholinesterase inhibitor on β-amyloid-induced the injury of neurite outgrowth via regulating axon guidance related genes expression in neuronal cells., PMID:23119107
Evaluation of Eph receptor and ephrin expression within the human cornea and limbus., PMID:23247085
ADAM12-cleaved ephrin-A1 contributes to lung metastasis., PMID:23686306
Expression of the EphA1 protein is associated with Fuhrman nuclear grade in clear cell renal cell carcinomas., PMID:26261568
Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab., PMID:26854735
EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells., PMID:28560458
Glycoengineering of EphA4 Fc leads to a unique, long-acting and broad spectrum, Eph receptor therapeutic antagonist., PMID:28747680
A potential role for Eph receptor signalling during migration of corneal endothelial cells., PMID:29476773
Serum biomarker panels for the diagnosis of gastric cancer., PMID:30873760
Inhibition of EphA/Ephrin-A signaling using genetic and pharmacologic approaches improves recovery following traumatic brain injury in mice., PMID:31319723
A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease., PMID:32296418
Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains., PMID:34508727
Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs., PMID:36806315
For research use only. Not for human or drug use.
