Catalog No.
PHE65101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ARRB1 (Asp3-Thr246).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ARRB1, Beta-arrestin-1, Non-visual arrestin-2, ARR1, Arrestin beta-1
Purification
Purified by antigen affinity column.
Accession
P49407
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Anti-ATR001 monoclonal antibody ameliorates atherosclerosis through beta-arrestin2 pathway., PMID:33516876
Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor., PMID:32555462
Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein-coupled receptors., PMID:32439801
Arrestin-β-1 Physically Scaffolds TSH and IGF1 Receptors to Enable Crosstalk., PMID:31127272
Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses., PMID:28842433
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer., PMID:24837709
β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism., PMID:24502978
Antidepressant-induced differential ubiquitination of β-arrestins 1 and 2 in mononuclear leucocytes of patients with depression., PMID:23672745
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide., PMID:23604254
Pharmacological blockade of a β(2)AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model., PMID:23287463
Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation., PMID:21855149
β-Arrestin 1 modulates functions of autoimmune T cells from primary biliary cirrhosis patients., PMID:21243522
ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors., PMID:21212384
Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs., PMID:20799926
Selective modulation of follicle-stimulating hormone signaling pathways with enhancing equine chorionic gonadotropin/antibody immune complexes., PMID:20332198
Visual Arrestin 1 contributes to cone photoreceptor survival and light adaptation., PMID:20019357
Dephosphorylation of beta-arrestin 1 in glioblastomas., PMID:19404096
Functional comparisons of visual arrestins in rod photoreceptors of transgenic mice., PMID:17460248
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation., PMID:16407241
Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor., PMID:16183993
Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain., PMID:15514408
beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport., PMID:11546805
Insulin and insulin-like growth factor I receptors utilize different G protein signaling components., PMID:11278773
Upregulation of G protein-linked receptor kinases with advancing age in rat aorta., PMID:11171671
Analysis of the C-terminal tail of the rat thyrotropin-releasing hormone receptor-1 in interactions and cointernalization with beta-arrestin 1-green fluorescent protein., PMID:11160875
Predominant presence of beta-arrestin-1 in small sensory neurons of rat dorsal root ganglia., PMID:10501467
A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes., PMID:9892661
Beta-arrestin and arrestin are recognized by autoantibodies in sera from multiple sclerosis patients., PMID:8475065
For research use only. Not for human or drug use.
