Catalog No.
PHE99101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CTSC (Leu231-Leu463).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Dipeptidyl peptidase 1, Dipeptidyl peptidase I exclusion domain chain, DPPI, Cathepsin J, Dipeptidyl transferase, Dipeptidyl peptidase I heavy chain, CTSC, Dipeptidyl peptidase I, Dipeptidyl peptidase I light chain, CPPI, Cathepsin C, DPP-I
Purification
Purified by antigen affinity column.
Accession
P53634
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Cathepsin C in health and disease: from structural insights to therapeutic prospects., PMID:39164687
Cathepsin C promotes colorectal cancer metastasis by regulating immune escape through upregulating CSF1., PMID:36916928
Novel compound heterozygous mutation in CTSC gene with response to ustekinumab., PMID:36740595
Regulatory T-cells-related signature for identifying a prognostic subtype of hepatocellular carcinoma with an exhausted tumor microenvironment., PMID:36189226
CREG1 promotes lysosomal biogenesis and function., PMID:33966596
Abrogation of cathepsin C by Helicobacter pylori impairs neutrophil activation to promote gastric infection., PMID:30596522
Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate., PMID:27455414
Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F., PMID:26247631
Identification and characterization of the interactive proteins with cytotoxic T-lymphocyte antigen-2α., PMID:25514977
Long-term change of disease behavior in Papillon-Lefèvre syndrome: seven years follow-up., PMID:25497043
Novel compound heterozygous mutations in CTSC gene cause Papillon-Lefèvre syndrome with high serum immunoglobulin E., PMID:25450092
HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels., PMID:24833610
Late stage cathepsin C, CXCL13 and Ki-67 overexpression correlate with regional neuropathology in a BSE transgenic murine model., PMID:22789860
Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis., PMID:22241891
High immunoglobulin E in a Chinese Papillon-Lefèvre syndrome patient with novel compound mutations of cathepsin C., PMID:22221209
Expression and purification of active recombinant cathepsin C (dipeptidyl aminopeptidase I) of kuruma prawn Marsupenaeus japonicus in insect cells., PMID:19707514
Immediate upregulation of proteins belonging to different branches of the apoptotic cascade in the retina after optic nerve transection and optic nerve crush., PMID:18775855
For research use only. Not for human or drug use.
