Catalog No.
PHA71301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CA12 (Ala25-Leu302).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Carbonate dehydratase XII, Carbonic anhydrase XII, Tumor antigen HOM-RCC-3.1.3, CA-XII, Carbonic anhydrase 12, CA12
Purification
Purified by antigen affinity column.
Accession
O43570
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors., PMID:35057692
Carbonic Anhydrase XII is a Clinically Significant, Molecular Tumor-Subtype Specific Therapeutic Target in Glioma with the Potential to Combat Invasion of Brain Tumor Cells., PMID:33692626
Frequency of BRCA1 and BRCA2 Mutations in Individuals with Breast and Ovarian Cancer in a Chinese Hakka Population Using Next-Generation Sequencing., PMID:32101877
Humanized Monoclonal Antibody Blocking Carbonic Anhydrase 12 Enzymatic Activity Leads to Reduced Tumor Growth In Vitro., PMID:31366496
α-Imaging Confirmed Efficient Targeting of CD45-Positive Cells After 211At-Radioimmunotherapy for Hematopoietic Cell Transplantation., PMID:26338894
Esterase activity of carbonic anhydrases serves as surrogate for selecting antibodies blocking hydratase activity., PMID:25775095
Predicting degree of benefit from adjuvant trastuzumab in NSABP trial B-31., PMID:24262440
Reagents for astatination of biomolecules. 6. An intact antibody conjugated with a maleimido-closo-decaborate(2-) reagent via sulfhydryl groups had considerably higher kidney concentrations than the same antibody conjugated with an isothiocyanato-closo-decaborate(2-) reagent via lysine amines., PMID:22296587
Serum anti-p53 antibody detection in carcinomas and the predictive values of serum p53 antibodies, carcino-embryonic antigen and carbohydrate antigen 12-5 in the neoadjuvant chemotherapy treatment for III stage non-small cell lung cancer patients., PMID:21277290
The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease., PMID:20886222
Reagents for astatination of biomolecules. 4. Comparison of maleimido-closo-decaborate(2-) and meta-[(211)At]astatobenzoate conjugates for labeling anti-CD45 antibodies with [(211)At]astatine., PMID:19731929
[Preparation and evaluation of a time-resolved fluoroimmunoassay kit for CA50 determination]., PMID:17649634
Association of apoptosis-related microsatellite polymorphisms on chromosome 1q in Taiwanese systemic lupus erythematosus patients., PMID:16412052
[Time-resolved fluoroimmunoassay of carcino-embryonic antigen and preparation of its diagnostic reagent]., PMID:16388762
[Preparation of time-resolved fluoroimmunoassay kit for human alpha-fetoprotein detection]., PMID:15772001
Simple repeat replacements support similar functions of distinct repeats in inter-species mRNA homologs., PMID:15019980
Comparable levels of Ca-ATPase inhibition by phospholamban in slow-twitch skeletal and cardiac sarcoplasmic reticulum., PMID:12403631
The chaperone GroEL is required for the final assembly of the molybdenum-iron protein of nitrogenase., PMID:11331775
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast., PMID:11238049
Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer., PMID:11238039
A novel anti-Thy-1 (CD90) monoclonal antibody induces apoptosis in mouse malignant T-lymphoma cells in spite of inducing bcl-2 expression., PMID:8635872
Canine lymphoma: immunocytochemical analysis of fine-needle aspiration biopsy., PMID:8801714
Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cells., PMID:7743522
Apoptosis inhibition by anti-M(r) 23,000 (Thy-1) monoclonal antibodies without inducing bcl-2 expression., PMID:7794803
Apoptosis of T lymphoma cells and its inhibition by monoclonal antibodies against cell surface adhesion molecules., PMID:8983066
A novel stage-specific differentiation antigen is expressed on mouse testicular germ cells during early meiotic prophase., PMID:8286583
Suppression of T-lymphoma cell apoptosis by monoclonal antibodies raised against cell surface adhesion molecules., PMID:8402694
[Lymphatic metastasis and cell adhesion, growth and growth inhibition]., PMID:8439186
Effect of chronic treatment with recombinant interleukin-2 on the central nervous system of adult and old mice., PMID:1446238
Neuronal injury and expression of 72-kDa heat-shock protein after forebrain ischemia in the rat., PMID:1792866
[CA-12 tumor marker values in serum following radioimmuno-scintigraphy]., PMID:2079306
Binding of Clostridium botulinum type C neurotoxin to different neuroblastoma cell lines., PMID:2535834
Ontogeny of the type 2 glucocorticoid receptor in discrete rat brain regions: an immunocytochemical study., PMID:3409041
A clinical evaluation of monoclonal (CA19-9, CA50, CA12-5) and polyclonal (CEA, TPA) antibody-defined antigens for the diagnosis of pancreatic cancer., PMID:3163149
Antigenic relationship between human and animal adenovirus hexons determined by means of monoclonal antibodies directed against bovine adenovirus type 2 hexon., PMID:2455494
Immunocytochemical study on the intracellular localization of the type 2 glucocorticoid receptor in the rat brain., PMID:3319051
The structural relation between the antigenic determinants to monoclonal antibodies and binding sites to rat brain synaptosomes and GT1b ganglioside in Clostridium botulinum type C neurotoxin., PMID:2581939
For research use only. Not for human or drug use.
