Catalog No.
PHC08301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KRT1 (Glu370-Glu489).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
K1, KRT1, Type-II keratin Kb1, Hair alpha protein, Cytokeratin-1, Keratin-1, CK-1, KRTA, Keratin, type II cytoskeletal 1, 67 kDa cytokeratin
Purification
Purified by antigen affinity column.
Accession
P04264
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
First successful treatment of epidermolytic Ichthyosis with Vunakizumab: A Case Report., PMID:40453098
Keratin 1 modulates intestinal barrier and immune response via kallikrein kinin system in ulcerative colitis., PMID:39958441
Associations of serum keratin 1 with thyroid function and immunity in Graves' disease., PMID:38019813
Study of pathological processes of meibomian gland dysfunction by in vitro culture airlifting conditions., PMID:37216482
Gene expression profiling of laminin α3-blocked keratinocytes reveals an immune-independent mechanism of blistering., PMID:34796550
Post Zygotic, Somatic, Deletion in KERATIN 1 V1 Domain Generates Structural Alteration of the K1/K10 Dimer, Producing a Monolateral Palmar Epidermolytic Nevus., PMID:34199056
Arginine- but not alanine-rich carboxy-termini trigger nuclear translocation of mutant keratin 10 in ichthyosis with confetti., PMID:31638346
Type XVIII Collagen Modulates Keratohyalin Granule Formation and Keratinization in Oral Mucosa., PMID:31554264
Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches., PMID:31244373
Optimisation of a serum albumin removal protocol for use in a proteomic study to identify the protein biomarkers for silent gastric ulceration in horses., PMID:30250392
Analysis of Sera of Recipients with Allograft Rejection Indicates That Keratin 1 Is the Target of Anti-Endothelial Antibodies., PMID:28265584
Keratin 1 plays a critical role in golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail., PMID:25605727
Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion., PMID:24398033
Tricholemmoma and clear cell squamous cell carcinoma (associated with Bowen's disease): immunohistochemical profile in comparison to normal hair follicles., PMID:22452951
Mapping of a neutralizing epitope in the surface envelope protein of porcine endogenous retrovirus subgroup B., PMID:21228129
MUC16 as a sensitive and specific marker for epithelial downgrowth., PMID:21060041
Disturbed keratin expression and distinct genotype of ichthyosis hystrix Lambert type., PMID:20605767
New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma., PMID:18647305
Early keratinocyte differentiation on micropillar interfaces., PMID:17297992
Fluorescence-based methods for studying intermediate filaments., PMID:15646623
Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures., PMID:15159456
Cis-regulatory elements of the mouse Krt1.12 gene., PMID:11951085
Cytokeratins 8 and 19 in the mouse placental development., PMID:11062258
Keratin 12-deficient mice have fragile corneal epithelia., PMID:8977471
For research use only. Not for human or drug use.
