Anti-SP1 Polyclonal Antibody

Catalog No.

PHC29701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SP1 (Leu260-Ala591).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

SP1, TSFP1, Transcription factor Sp1

Purification

Purified by antigen affinity column.

Accession

P08047

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

BAP1-mediated ubiquitination inhibition and CAS6/AXL signaling activation in bladder cancer progression., PMID:40330545

Virus-induced RGMa expression drives neurodegeneration in HTLV-1-associated myelopathy., PMID:40305434

Inhibition of tumour necrosis factor alpha by Etanercept attenuates Shiga toxin-induced brain pathology., PMID:39920757

YAP/TEAD4/SP1-induced VISTA expression as a tumor cell-intrinsic mechanism of immunosuppression in colorectal cancer., PMID:39875519

[Diagnostic values of anti-salivary gland protein-1 antibody combined with anti-parotid secretory protein antibody for Sjögren's syndrome]., PMID:39397464

SP1 undergoes phase separation and activates RGS20 expression through super-enhancers to promote lung adenocarcinoma progression., PMID:38976739

Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment., PMID:38885318

Exploration of the Shared Gene Signatures and Molecular Mechanisms between Chronic Bronchitis and Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis: Evidence from Transcriptome Data., PMID:38847168

[Comparative immunohistochemistry study of different antibodies clones for detection of breast cancer markers (estrogen receptor, progesterone receptor, HER2/neu, Ki-67)]., PMID:38591902

Immune response enhancement by dietary supplementation with Caesalpinia sappan extract in weaned pigs challenged with porcine reproductive and respiratory syndrome virus., PMID:38515094

HDAC Inhibition Induces CD26 Expression on Multiple Myeloma Cells via the c-Myc/Sp1-mediated Promoter Activation., PMID:38284882

FSH Is Responsible for Androgen Deprivation Therapy-Associated Atherosclerosis in Mice by Exaggerating Endothelial Inflammation and Monocyte Adhesion., PMID:38205641

Nicotinic acetylcholine receptor activation induces BACE1 transcription via the phosphorylation and stabilization of nuclear SP1., PMID:38110001

Humoral Response to SARS-COV-2 Vaccination in Patients with Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder: A Real-World Study., PMID:38097868

SIRPA enhances osteosarcoma metastasis by stabilizing SP1 and promoting SLC7A3-mediated arginine uptake., PMID:37769797

ER and COX2 expression in endometrial hyperplasia processes., PMID:37603513

Immune response after SARS-CoV-2 vaccination in patients with inflammatory immune-mediated diseases receiving immunosuppressive treatment., PMID:37598192

Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop., PMID:37481646

Knockdown of versican 1 in lung fibroblasts aggravates Lipopolysaccharide-induced acute inflammation through up-regulation of the SP1-Toll-like Receptor 2-NF-κB Axis: a potential barrier to promising Versican-targeted therapy., PMID:37311354

Immunoaffinity biosensors for the detection of SARS-CoV-1 using screened Fv-antibodies from an autodisplayed Fv-antibody library., PMID:37301177

Substance P analogs devoid of key residues fail to activate human mast cells via MRGPRX2., PMID:37228611

The downregulation of HSP90-controlled CRALBP expression is associated with age-related vision attenuation., PMID:36826429

Case-Control Study Examining the Composition of the Gut Microbiome in Individuals With and Without Immune-Mediated Dry Eye., PMID:36729650

Identification and characterization of a flexile G-quadruplex in the distal promoter region of stemness gene REX1., PMID:36649868

New insights into antibody levels against SARS-CoV-2 for healthcare personnel vaccinated with tozinameran (Comirnaty)., PMID:36327310

Gene Profiling of a 3D Psoriatic Skin Model Enriched in T Cells: Downregulation of PTPRM Promotes Keratinocyte Proliferation through Excessive ERK1/2 Signaling., PMID:36139479

HIV-1 Vpr suppresses expression of the thiazide-sensitive sodium chloride co-transporter in the distal convoluted tubule., PMID:36129874

An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion., PMID:35951767

Candidate autoantibodies for primary Sjögren's syndrome: where are they now?, PMID:35616578

Inducing Synergistic DNA Damage by TRIP13 and PARP1 Inhibitors Provides a Potential Treatment for Hepatocellular Carcinoma., PMID:35517402

Upregulation of Endothelial DKK1 (Dickkopf 1) Promotes the Development of Pulmonary Hypertension Through the Sp1 (Specificity Protein 1)/SHMT2 (Serine Hydroxymethyltransferase 2) Pathway., PMID:35249365

Improved immunologic response to COVID-19 vaccine with prolonged dosing interval in haemodialysis patients., PMID:35244289

Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts., PMID:35181688

High expression of progesterone receptor may be an adverse prognostic factor in oestrogen receptor-negative/progesterone receptor-positive breast cancer: results of comprehensive re-evaluation of multi-institutional case series., PMID:35074178

Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling., PMID:35027670

Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression., PMID:34968486

Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches., PMID:34843493

TPH1 and 5-HT7 Receptor Overexpression Leading to Gemcitabine-Resistance Requires Non-Canonical Permissive Action of EZH2 in Pancreatic Ductal Adenocarcinoma., PMID:34771469

Encoding hierarchical assembly pathways of proteins with DNA., PMID:34593642

Comment on Favresse et al. Persistence of Anti-SARS-CoV-2 Antibodies Depends on the Analytical Kit: A Report for Up to 10 Months after Infection. Microorganisms 2021, 9, 556., PMID:34442865

NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis., PMID:34421354

The Diagnostic Performance of Early Sjögren's Syndrome Autoantibodies in Juvenile Sjögren's Syndrome: The University of Florida Pediatric Cohort Study., PMID:34249010

LMCD1 antisense RNA 1 is a newly identified long noncoding RNA., PMID:34232945

An explicitly designed paratope of amyloid-β prevents neuronal apoptosis in vitro and hippocampal damage in rat brain., PMID:34164050

COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells., PMID:34117361

miR-9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC., PMID:34062049

Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound., PMID:33819507

A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis., PMID:33754057

Myocardin-related transcription factor A regulates integrin beta 2 transcription to promote macrophage infiltration and cardiac hypertrophy in mice., PMID:33752236

Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase., PMID:33686291

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