Research Grade Lulizumab (DHC83401)

Catalog No.

DHC83401

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

V-kappa

Clonality

Monoclonal

Target

CD28, TP44, T-cell-specific surface glycoprotein CD28

Concentration

0.51 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10747

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Lulizumab

Preoperative carfilzomib and lulizumab based desensitization prolongs graft survival in a sensitized non-human primate model, PMID: 32898569

Pharmacokinetic, Pharmacodynamic, and Safety Profile of a Novel Anti-CD28 Domain Antibody Antagonist in Healthy Subjects, PMID: 27402064

Advances in the treatment of cutaneous lupus erythematosus, PMID: 27252259

Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699, PMID: 26442523

Document Download

Research Grade Lulizumab.pdf