Catalog No.
YMK84401
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Met1-Thr169
Predicted molecular weight
31.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9DCR4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EP300-interacting inhibitor of differentiation 1, CREBBP/EP300 inhibitory protein 1, E1A-like inhibitor of differentiation 1, EID-1, Eid1, Cri1
EID1 promotes the response to canopy shade in Arabidopsis thaliana by repressing the action of phytochrome A., PMID:38152059
DNA methylation and general psychopathology in childhood: an epigenome-wide meta-analysis from the PACE consortium., PMID:36385171
Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family., PMID:35716663
Based on a Self-Feeder Layer, a Novel 3D Culture Model of Human ADSCs Facilitates Trans-Differentiation of the Spheroid Cells into Neural Progenitor-Like Cells Using siEID3 with a Laminin/Poly-d-lysine Matrix., PMID:33668931
Fbxo21 regulates the epithelial-to-mesenchymal transition through ubiquitination of Nr2f2 in gastric cancer., PMID:33531987
JUNB-FBXO21-ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy., PMID:33450132
Sucralose causes non-selective CD4 and CD8 lymphotoxicity via probable regulation of the MAPK8/APTX/EID1 genes: An in vitro/in silico study., PMID:32542867
EID1 suppresses lipid accumulation by inhibiting the expression of GPDH in 3T3-L1 preadipocytes., PMID:32056205
Transcriptome profiling in Eid1-KO mice brain shows that Eid1 links cell proliferation in the brain., PMID:31381951
Microarray analysis of cartilage: comparison between damaged and non-weight-bearing healthy cartilage., PMID:31142155
EID1 plays a crucial role in proliferation of neural stem cell., PMID:30926163
Mutations in EID1 and LNK2 caused light-conditional clock deceleration during tomato domestication., PMID:29789384
Regulation of human subcutaneous adipocyte differentiation by EID1., PMID:26643909
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21., PMID:26631746
Domestication selected for deceleration of the circadian clock in cultivated tomato., PMID:26569124
Protein Palmitoylation Regulates Neural Stem Cell Differentiation by Modulation of EID1 Activity., PMID:26497028
FBXO21 mediates the ubiquitylation and proteasomal degradation of EID1., PMID:26085330
Progranulin Deficiency Reduces CDK4/6/pRb Activation and Survival of Human Neuroblastoma SH-SY5Y Cells., PMID:25377796
E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network., PMID:24619556
Structural insights into gene repression by the orphan nuclear receptor SHP., PMID:24379397
Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability., PMID:24167073
[F-box proteins of plants and their various roles]., PMID:22844772
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease., PMID:22186421
Lentivirus-mediated RNA interference of E2F-1 suppresses Tca8113 cell proliferation., PMID:22076063
Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924., PMID:21873567
EDL3 is an F-box protein involved in the regulation of abscisic acid signalling in Arabidopsis thaliana., PMID:21831845
The switch from pRb/p105 to Rb2/p130 in DNA damage and cellular senescence., PMID:21465484
Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families., PMID:21364888
A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs., PMID:20585629
EID1-induces brown-like adipocyte traits in white 3T3-L1 pre-adipocytes., PMID:20541531
Novel polymorphisms of nuclear receptor SHP associated with functional and structural changes., PMID:20516075
MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1., PMID:20486779
Clinicopathological significance of cell cycle regulatory factors and differentiation-related factors in pancreatic neoplasms., PMID:20335778
HY253, a novel decahydrofluorene analog, from Aralia continentalis, induces cell cycle arrest at the G1 phase and cytochrome c-mediated apoptosis in human lung cancer A549 cells., PMID:20219657
The histidine kinase-related domain of Arabidopsis phytochrome a controls the spectral sensitivity and the subcellular distribution of the photoreceptor., PMID:19403732
E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells., PMID:19276448
Expression patterns of cyclins D1, E and cyclin-dependent kinase inhibitors p21waf1/cip1, p27kip1 in colorectal carcinoma: correlation with other cell cycle regulators (pRb, p53 and Ki-67 and PCNA) and clinicopathological features., PMID:19143860
Malignant pleural mesothelioma-targeted CREBBP/EP300 inhibitory protein 1 promoter system for gene therapy and virotherapy., PMID:18757427
The Prader-Willi syndrome protein necdin interacts with the E1A-like inhibitor of differentiation EID-1 and promotes myoblast differentiation., PMID:18557765
HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function., PMID:18367227
Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death., PMID:18235223
EID-1 interacts with orphan nuclear receptor SF-1 and represses its transactivation., PMID:18182853
Male and female breast cancer--differences in DNA ploidy, p21 and p53 expression reinforce the possibility of distinct pathways of oncogenesis., PMID:18087196
Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture., PMID:17996702
G1 cell cycle arrest by amlodipine, a dihydropyridine Ca2+ channel blocker, in human epidermoid carcinoma A431 cells., PMID:17217918
RB, the conductor that orchestrates life, death and differentiation., PMID:16936739
p16, retinoblastoma (pRb), and cyclin D1 protein expression in human endometriotic and adenomyotic lesions., PMID:16616093
Requirement of E7 oncoprotein for viability of HeLa cells., PMID:16500131
Functional analysis of EID1, an F-box protein involved in phytochrome A-dependent light signal transduction., PMID:16412087
Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner., PMID:16343421