Catalog No.
YHJ81304
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala1365-Pro1497
Predicted molecular weight
42.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UMD9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2, 120 kDa linear IgA disease antigen, 120 kDa linear IgA dermatosis antigen, Linear IgA disease antigen 1, LAD-1, 97 kDa linear IgA disease antigen, 97 kDa linear IgA bullous dermatosis antigen, 97 kDa LAD antigen, 97-LAD, Linear IgA bullous disease antigen of 97 kDa, LABD97, COL17A1, BP180, BPAG2
Evaluation of tumor targets selected from public genomic databases for imaging of pancreatic ductal adenocarcinoma., PMID:40379788
Identifying six single nucleotide variants in the COL17A1 gene that alter RNA splicing: database analysis and minigene assays., PMID:40181146
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII., PMID:40066849
Novel strategy for hair regeneration: Exosomes and collagenous sequences of human a1(XVII) chain enhance hair follicle stem cell activity by regulating the hsa-novel-238a-CASP9 axis., PMID:40010561
Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4., PMID:39907925
ADAM10 Expression by Ameloblasts Is Essential for Proper Enamel Formation., PMID:39684894
Non-Herlitz junctional epidermolysis bullosa in a Native American newborn., PMID:39636096
Caviar extract inhibits skin photoaging by activating skin stem cells through NF-κB/MMPs/COL17A1 axis., PMID:39627162
Construction of a novel model based on PVT1-MYC duet-related genes for predicting survival and characterization of the tumor microenvironment in pancreatic cancer., PMID:39376555
Expression, DNA methylation pattern and transcription factor EPB41L3 in gastric cancer: a study of 262 cases., PMID:39354571
Junctional Epidermolysis Bullosa in Sprague Dawley Rats Caused by a Frameshift Mutation of Col17a1 Gene., PMID:39265891
Heterozygous COL17A1 variants are a frequent cause of amelogenesis imperfecta., PMID:39214682
The Deubiquitinase USP22-Stabilized COL17A1 Promotes Lung Adenocarcinoma Progression., PMID:39143031
[Clinical and bioinformatics analysis of the relationship between LAMA3 DNA methylation expression and platinum resistance and prognosis in epithelial ovarian cancer]., PMID:38951081
[A case of Neonatal generalized atrophic benign epidermolysis bullosa due to variants of COL17A1 gene]., PMID:38818561
Collagen XVII promotes dormancy of colorectal cancer cells by activating mTORC2 signaling., PMID:38795810
Collagen 17A1 in the Urothelium Regulates Epithelial Cell Integrity and Local Immunologic Responses in Obstructive Uropathy., PMID:38768778
Dab2 (Disabled-2), an adaptor protein, regulates self-renewal of hair follicle stem cells., PMID:38702433
The Molecular Characteristics and Therapeutic Implications of O-Glycan Synthesis in Pancreatic Cancer by Integrating Transcriptome and Single-Cell Data., PMID:38659264
Strategy for the Optimization of Read-Through Therapy for Junctional Epidermolysis Bullosa with COL17A1 Nonsense Mutation., PMID:38522573
On- and off-target effects of paired CRISPR-Cas nickase in primary human cells., PMID:38459694
Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment., PMID:38401525
IC3D Classification of Corneal Dystrophies-Edition 3., PMID:38359414
Aspirin-exacerbated respiratory disease is associated with variants in filaggrin, epithelial integrity, and cellular interactions., PMID:38317805
NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1., PMID:38175757
Genotype-Phenotype Correlation in Junctional Epidermolysis Bullosa: Signposts to Severity., PMID:38157931
Heterozygous COL17A1 variants are a frequent cause of amelogenesis imperfecta., PMID:37979963
METTL14-mediated N6-methyladenosine modification of Col17a1/Itgα6/Itgβ4 governs epidermal homeostasis., PMID:37951776
Digenic inheritance accounts for phenotypic variability in amelogenesis imperfecta., PMID:37937686
Independent COL17A1 Variants in Cats with Junctional Epidermolysis Bullosa., PMID:37895184
Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum., PMID:37883475
Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice., PMID:37796769
Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment., PMID:37688308
Molecular insights of human skin epidermal and dermal aging., PMID:37661473
Bazi Bushen alleviates skin senescence by orchestrating skin homeostasis in SAMP6 mice., PMID:37614114
Identification of potential hub genes associated with atopic dermatitis-like recombinant human epidermal model using integrated transcriptomic and proteomic analysis., PMID:37540585
Native Autoantigen Complex Detects Pemphigoid Autoantibodies., PMID:36992950
A Novel Fluorescence-Based Screen of Gene Editing Molecules for Junctional Epidermolysis Bullosa., PMID:36982270
Mutational analysis of epidermolysis bullosa in Taiwan by whole-exome sequencing complemented by RNA sequencing: a series of 77 patients., PMID:36578049
ADAM10: Possible functions in enamel development., PMID:36505044
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization., PMID:36435441
Targeted NGS in Diagnostics of Genodermatosis Characterized by the Epidermolysis Bullosa Symptom Complex in 268 Russian Children., PMID:36430820
Dipeptidyl Peptidase-4 Inhibitor-Related Bullous Pemphigoid: Clinical, Laboratory, and Histological Features, and Possible Pathogenesis., PMID:36430582
Genotype and phenotype correlations in 441 patients with epidermolysis bullosa from China., PMID:36287101
A necroptosis related prognostic model of pancreatic cancer based on single cell sequencing analysis and transcriptome analysis., PMID:36275722
COL17A1 facilitates tumor growth and predicts poor prognosis in pancreatic cancer., PMID:36191371
COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa., PMID:36091706
Palmitoyl‑RGD promotes the expression of dermal‑epidermal junction components in HaCaT cells., PMID:36043531
Absence of NC14A Domain of COLXVII/BP180 in Mice Results in IL-17‒Associated Skin Inflammation., PMID:35985497
Bioinformatics Analysis Identifies Potential Related Genes in the Pathogenesis of Intrauterine Fetal Growth Retardation., PMID:35923419
For research use only. Not for human or drug use.
