Catalog No.
EMM04001
Expression system
Insect Cells
Species
Mus musculus (Mouse)
Protein length
[Glu24-Thr219] & [Gly28-Lys224]
Predicted molecular weight
164.2kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6SR48 & Q6SR47
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
H-2 class II histocompatibility antigen, A-D alpha chain, H2-Aa, H2-Ea, H-2 class II histocompatibility antigen, A-D beta chain, H2-Ab1, Rmcs2
Optimal human pathogenic TH2 cell effector function requires local epithelial cytokine signaling., PMID:33662368
Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334-352 that induces autoimmune myocarditis in A/J mice., PMID:26422020
Characterization of a New Epitope of IRBP That Induces Moderate to Severe Uveoretinitis in Mice With H-2b Haplotype., PMID:26284549
Postnatal exposure to a high-carbohydrate diet interferes epigenetically with thyroid hormone receptor induction of the adult male rat skeletal muscle glucose transporter isoform 4 expression., PMID:25086780
On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes., PMID:22805744
Detection of autoreactive CD4 T cells using major histocompatibility complex class II dextramers., PMID:21767394
Vaccination with a Plasmodium chabaudi adami multivalent DNA vaccine cross-protects A/J mice against challenge with P. c. adami DK and virulent Plasmodium chabaudi chabaudi AS parasites., PMID:18062974
The involvement of FcR mechanisms in antibody-mediated rejection., PMID:18049118
Histocompatible embryonic stem cells by parthenogenesis., PMID:17170255
Active role of chimerism in transplantation tolerance induced by antilymphocyte serum, sirolimus, and bone-marrow-cell infusion., PMID:15385800
Leishmania-induced inhibition of macrophage antigen presentation analyzed at the single-cell level., PMID:14662874
Passive transfer of alloantibodies restores acute cardiac rejection in IgKO mice., PMID:11330533
The alloreactive and self-restricted CD4+ T cell response directed against a single MHC class II/peptide combination., PMID:10903728
H2-E transgenic class II-negative mice can distinguish self from nonself in susceptibility to heterologous thyroglobulins in autoimmune thyroiditis., PMID:10541803
Low responsiveness to immunization with immunoglobulin E/antigen and immunoglobulin G/antigen complexes in H-2Ab mice., PMID:10404051
Drug-induced inhibition of insulin recognition by T-cells: the antirheumatic drug aurothiomalate inhibits MHC binding of insulin peptide., PMID:10395197
Peptide dependency of alloreactive CD4+ T cell responses., PMID:10221647
The genotype determines the B cell response in mercury-treated mice., PMID:9693280
Cloning and characterization of a new swine MHC (SLA) class II DQB allele., PMID:9673944
Genetic control of the immune response to HIV type 1 envelope glycoprotein 120 in mice: effects of MHC and transgenic human CD4., PMID:9671218
The mouse H-2A region influences the envelope gene structure of tumor-associated murine leukemia viruses., PMID:9557684
Efficient presentation of endogenous superantigen by H-2Aq., PMID:9541599
MHC class II Ab diabetogenic residue 57 Asp/non-Asp dimorphism influences T-cell recognition and selection., PMID:9435340
Identification of a peptide inducing experimental autoimmune uveoretinitis (EAU) in H-2Ak-carrying mice., PMID:9486417
Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice., PMID:9410904
Allelic polymorphisms at the H-2A and HLA-DQ loci influence the response of murine lymphocytes to the Mycoplasma arthritidis superantigen MAM., PMID:9317026
Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice., PMID:8920873
A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak., PMID:8752926
Developmental expression of insulin-like growth factor II receptor (IGF-IIR) in congenic mouse embryonic lungs: correlation between IGF-IIR mRNA and protein levels and heterochronic lung development., PMID:9115713
Unique role of thyroxine in T cell recognition of a pathogenic peptide in experimental autoimmune thyroiditis., PMID:8625966
Presentation of a self-peptide for in vivo tolerance induction of CD4+ T cells is governed by a processing factor that maps to the class II region of the major histocompatibility complex locus., PMID:7595218
Exacerbated autoimmunity associated with a T helper-1 cytokine profile shift in H-2E-transgenic mice., PMID:7489754
Immunization with a single T helper cell epitope abrogates Friend virus-induced early erythroid proliferation and prevents late leukemia development., PMID:7541823
The CORT-GR signal transduction pathway and CORT-induced cleft palate in H-2 congenic mice., PMID:7635930
Immune response to porins isolated from Salmonella typhi in different mouse strains., PMID:8845667
Protective role of major histocompatibility complex class II Ebd transgene on collagen-induced arthritis., PMID:7931088
Cathepsin D, but not cathepsin B, releases T cell stimulatory fragments from lysozyme that are functional in the context of multiple murine class II MHC molecules., PMID:8088334
Alterations in major histocompatibility complex association of myocarditis induced by coxsackievirus B3 mutants selected with monoclonal antibodies to group A streptococci., PMID:8202524
Analysis of the humoral response elicited in mice by a chimeric peptide representing variable segments I and IV of the major outer membrane protein of Chlamydia trachomatis., PMID:7518628
The role of class II molecules in Mls 1a recognition by CD4+ T cells is independent of the CD4 molecule., PMID:7903065
H-2 gene complex and corticosteroid responsiveness: evidence that the corticosteroid hormone signal transduction pathway in the adult mouse lung is not associated with haplotype-specific responses to corticosteroids., PMID:8236324
Murine susceptibility to mercury. II. autoantibody profiles and renal immune deposits in hybrid, backcross, and H-2d congenic mice., PMID:8513597
MHC-specific graft-protective and delayed-type hypersensitivity (DTH) suppressive activity of a CD4+ CD8+, alpha beta T cell receptor (TCR) positive lymphoma isolated from a tolerant mouse., PMID:8406557
Murine susceptibility to mercury. I. Autoantibody profiles and systemic immune deposits in inbred, congenic, and intra-H-2 recombinant strains., PMID:1395135
Major histocompatibility complex-restricted recognition of retroviral superantigens by V beta 17+ T cells., PMID:1535369
Genetic control of immune responses in mice to synthetic peptides of a Streptococcus mutans surface protein antigen., PMID:1370433
A gene(s) within the H-2D region determines the development of toxoplasmic encephalitis in mice., PMID:1783431
Induction of protective immunity to Friend murine leukemia virus in genetic nonresponders to virus envelope protein., PMID:2033265
[Genetic control of antibody response to Actinobacillus actinomycetemcomitans in mice]., PMID:2066635
Class I MHC genes and CD8+ T cells determine cyst number in Toxoplasma gondii infection., PMID:2121825
For research use only. Not for human or drug use.
