Catalog No.
EHG09901
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Gly86-Gly244
Predicted molecular weight
21.90 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06643
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lymphotoxin-beta, LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3, LTB, TNFC, TNFSF3
A Recombinant Shigella flexneri Strain Expressing ETEC Heat-Labile Enterotoxin B Subunit Shows Promise for Vaccine Development via OMVs., PMID:39684252
Expression, purification and characterization of a novel triple fusion protein developed for the immunotherapy of survivin positive cancers., PMID:39396748
Long Non-Coding RNA AL928768.3 Promotes Rheumatoid Arthritis Fibroblast-Like Synoviocytes Proliferation, Invasion and Inflammation, While Inhibits Apoptosis Via Activating Lymphotoxin Beta Mediated NF-κB Signaling Pathway., PMID:37919527
Incorporation of Escherichia coli heat-labile enterotoxin B subunit into rabies virus particles enhances its immunogenicity in mice and dogs., PMID:40078911
Preparation of novel trivalent vaccine against enterotoxigenic Escherichia coli for preventing newborn piglet diarrhea., PMID:36576801
Protective Immunity Against Enterotoxigenic Escherichia coli by Oral Vaccination of Engineered Lactococcus lactis., PMID:34264362
Immunization with recombinant Erns-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus., PMID:34153721
Influence of the Draining Lymph Nodes and Organized Lymphoid Tissue Microarchitecture on Susceptibility to Intradermal Trypanosoma brucei Infection., PMID:32582198
Interindividual Variability in Lymphocyte Stimulation and Transcriptomic Response Predicts Mycophenolic Acid Sensitivity in Healthy Volunteers., PMID:32415749
Expression of Escherichia coli Heat-Labile Enterotoxin B Subunit in Centella (Centella asiatica (L.) Urban) via Biolistic Transformation., PMID:32101119
Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB Pathways., PMID:31624067
Lymphotoxin-β receptor-NIK signaling induces alternative RELB/NF-κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer., PMID:30488488
Expression of B subunit of E. coli heat-labile enterotoxin in the progenies of transgenic tobacco bred by crossing nuclear- and chloroplast-transgenic lines., PMID:30468854
Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice., PMID:30445013
Clinical aspects and polymorphisms in the LTA, TNFA, LTB genes and association with dental implant loss., PMID:30334603
An LTB-entrapped protein in PLGA nanoparticles preserves against enterotoxin of enterotoxigenic Escherichia coli., PMID:29922433
Reduced lymphotoxin-beta production by tumour cells is associated with loss of follicular dendritic cell phenotype and diffuse growth in follicular lymphoma., PMID:29665320
Entrapment of LTB protein in alginate nanoparticles protects against Enterotoxigenic Escherichia coli., PMID:29460309
Inactivation of TNF/LT locus alters mouse metabolic response to concentrated ambient PM2.5., PMID:28917655
Construction of an inactivated typhoid vaccine candidate expressing Escherichia coli heat-labile enterotoxin B subunit and evaluation of its immunogenicity in a murine model., PMID:28792376
Development of a novel recombinant LHRH fusion protein for therapy of androgen and estrogen dependent cancers., PMID:28410993
In-silico design, expression, and purification of novel chimeric Escherichia coli O157:H7 OmpA fused to LTB protein in Escherichia coli., PMID:28296951
Lymphotoxin-β Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer., PMID:28196873
Dendritic cells maintain dermal adipose-derived stromal cells in skin fibrosis., PMID:27721238
Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development., PMID:27478039
Ectopic expression of CXCL13, BAFF, APRIL and LT-β is associated with artery tertiary lymphoid organs in giant cell arteritis., PMID:27098405
Evaluation of Salmonella Gallinarum ghost formulated with Montanide™ ISA 70 VG adjuvant as a vaccine against fowl typhoid., PMID:26599088
Subunit Vaccine Preparation of Bovine Rotavirus and Its Efficacy in Mice., PMID:26412637
Novel mouse model to study T cell-dependent IgA induction in vivo., PMID:25790905
T lymphocytes maintain structure and function of fibroblastic reticular cells via lymphotoxin (LT)-B., PMID:25266629
Characterization of a Salmonella Typhimurium ghost carrying an adjuvant protein as a vaccine candidate for the protection of chickens against virulent challenge., PMID:25245884
Comparative evaluation of Salmonella Enteritidis ghost vaccines with a commercial vaccine for protection against internal egg contamination with Salmonella., PMID:25218296
Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas., PMID:25211095
Mechanism of the 24-hour rhythm of tumor necrosis factor-alpha formed by onset of rheumatoid arthritis., PMID:24517140
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma., PMID:24429703
Construction of a recombinant-attenuated Salmonella Enteritidis strain secreting Escherichia coli heat-labile enterotoxin B subunit protein and its immunogenicity and protection efficacy against salmonellosis in chickens., PMID:24176491
Gene expression in hippocampus as a function of differential trait anxiety levels in genetically heterogeneous NIH-HS rats., PMID:24095878
Enhanced protective immune responses against Salmonella Enteritidis infection by Salmonella secreting an Escherichia coli heat-labile enterotoxin B subunit protein., PMID:23856155
Adjuvant effect of Escherichia coli heat labile enterotoxin B subunit against internal egg contamination in domestic fowl immunised with a live Salmonella enterica serovar Enteritidis vaccine., PMID:23642467
Use of the wound-inducible NtQPT2 promoter from Nicotiana tabacum for production of a plant-made vaccine., PMID:22354474
Blocking lymphotoxin signaling abrogates the development of ectopic lymphoid tissue within cardiac allografts and inhibits effector antibody responses., PMID:21926237
Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction., PMID:21508326
[Transcriptional regulation of TNF/LT locus in immune cells]., PMID:21485497
Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation., PMID:21466787
Gene expression profile of cytokines in patients with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation with reduced conditioning., PMID:21211989
Enhancement of immune responses by an attenuated Salmonella enterica serovar Typhimurium strain secreting an Escherichia coli heat-labile enterotoxin B subunit protein as an adjuvant for a live Salmonella vaccine candidate., PMID:21159921
TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult., PMID:21135813
A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults., PMID:21029472
Role of the gut-associated and secondary lymphoid tissue in the induction of chronic colitis., PMID:20812332
Antibody against recombinant heat labile enterotoxin B subunit (rLTB) could block LT binding to ganglioside M1 receptor., PMID:22347560