Catalog No.
VHJ21901
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Secreted apoptosis-related protein 2, FRP-1, SARP2, SARP-2, sFRP-1, FRP, SFRP1, FRP1, Secreted frizzled-related protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8N474
Applications
Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0171
SFRP1 and SFRP2 jointly regulate normal and malignant hematopoietic progenitors by influencing mesenchymal cells in the hematopoietic niche., PMID:40446746
SFRP2 mediates Epstein-Barr virus and bladder cancer risk: a Mendelian randomization study and colocalization analysis., PMID:40016549
Validation and in vivo characterization of research antibodies for Moesin, CD44, Midkine, and sFRP-1., PMID:39444645
A guide to selecting high-performing antibodies for Secreted frizzled-related protein 1 (sFRP-1) for use in Western Blot and immunoprecipitation., PMID:39319244
Interleukin-19 in Bone Marrow Contributes to Bone Loss Via Suppressing Osteogenic Differentiation Potential of BMSCs in Old Mice., PMID:38502291
Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation., PMID:33493531
Local Wnt3a treatment restores bone regeneration in large osseous defects after surgical debridement of osteomyelitis., PMID:32424558
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis., PMID:31308530
Correlation between SFRP1 expression and clinicopathological parameters in patients with triple-negative breast cancer., PMID:31140870
Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options., PMID:30770859
sFRP1 has a biphasic effect on doxorubicin-induced cardiotoxicity in a cellular location-dependent manner in NRCMs and Rats., PMID:30377735
Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner., PMID:30177832
Analysis of the miRNA-mRNA-lncRNA network in human estrogen receptor-positive and estrogen receptor-negative breast cancer based on TCGA data., PMID:29518546
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists., PMID:29129759
Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells., PMID:28510269
The influence of tumor necrosis factor-α on the tumorigenic Wnt-signaling pathway in human mammary tissue from obese women., PMID:28402277
Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016., PMID:27294413
Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection., PMID:27193292
IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis., PMID:27165410
Induction of CXC chemokines in human mesenchymal stem cells by stimulation with secreted frizzled-related proteins through non-canonical Wnt signaling., PMID:26730270
Hippocampal Wnt3a is Necessary and Sufficient for Contextual Fear Memory Acquisition and Consolidation., PMID:24904070
Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway., PMID:24374650
Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors., PMID:24217964
Obesity associated alterations in the biology of adipose stem cells mediate enhanced tumorigenesis by estrogen dependent pathways., PMID:24176089
Neural stem cells inhibit melanin production by activation of Wnt inhibitors., PMID:24016750
Expression of SFRP Family Proteins in Human Keratoconus Corneas., PMID:23825088
Increased expression of secreted frizzled-related protein-1 and microtubule-associated protein light chain 3 in keratoconus., PMID:23449484
CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer., PMID:23049225
Receptor for advanced glycation end products inhibits proliferation in osteoblast through suppression of Wnt, PI3K and ERK signaling., PMID:22699121
Pαx6 expression in postmitotic neurons mediates the growth of axons in response to SFRP1., PMID:22359602
CpG island methylator phenotype in plasma is associated with hepatocellular carcinoma prognosis., PMID:22180715
Coordination of epithelial branching and salivary gland lumen formation by Wnt and FGF signals., PMID:21806977
Combination chemotherapy with ifosfamide, cisplatin, and etoposide for medulloblastoma: single-institute experience and differences in efficacy for subgroups of medulloblastoma., PMID:21590299
Resistance or sensitivity of Wilms' tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target., PMID:21472018
Effects of EpCAM overexpression on human breast cancer cell lines., PMID:21281469
Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin., PMID:20856206
Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation., PMID:20795789
Secreted frizzled-related protein 1 (SFRP1) is highly upregulated in keratoconus epithelium: a novel finding highlighting a new potential focus for keratoconus research and treatment., PMID:20447100
N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling., PMID:20011526
Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts., PMID:19734317
Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma., PMID:19690140
Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signaling., PMID:19342601
Wnt signaling as a therapeutic target for bone diseases., PMID:19335070
Myocilin is a modulator of Wnt signaling., PMID:19188438
Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice., PMID:19056741
Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma., PMID:18497987
The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells., PMID:18177422
[Epigenetic inactivation of the WNT antagonist SFRP1 in breast cancer]., PMID:18035687
Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation., PMID:17897439
Inhibition of SFRP1 reduces severity of periodontitis., PMID:17720858
For research use only. Not for human or drug use.
