Catalog No.
PHG17101
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DSC1 (Ala486-Asn686).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DSC1, Desmosomal glycoprotein 2/3, Desmocollin-1, DG2/DG3, Cadherin family member 1, CDHF1
Purification
Purified by antigen affinity column.
Accession
Q08554
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Combining sandblasting and pink anodisation of Ti implants as a promising method for improving fibroblast adhesion and immune response., PMID:39141321
Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162
Re-evaluating the prevalence of anti-desmocollin-1 IgA autoantibodies in canine pemphigus foliaceus., PMID:38820947
Pemphigus Autoantibodies to Desmocollin 3 but Not to Desmocollin 1 Directly Block Heterophilic Desmoglein/Desmocollin Transinteraction., PMID:38101510
Significance of anti-desmocollin autoantibodies in pemphigus., PMID:36578135
Subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma: A case report and literature review., PMID:35838241
Trunk-dominant and classic facial pemphigus foliaceus in dogs - comparison of anti-desmocollin-1 and anti-desmoglein-1 autoantibodies and clinical presentations., PMID:35670648
Gene expression profiling of laminin α3-blocked keratinocytes reveals an immune-independent mechanism of blistering., PMID:34796550
Open trial of Bruton's tyrosine kinase inhibitor (PRN1008) in the treatment of canine pemphigus foliaceus., PMID:32803903
Pemphigus Vulgaris and Foliaceus IgG Autoantibodies Directly Block Heterophilic Transinteraction between Desmoglein and Desmocollin., PMID:32142800
Efficacy of a Bruton's Tyrosine Kinase Inhibitor (PRN-473) in the treatment of canine pemphigus foliaceus., PMID:31899567
A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa., PMID:31281635
Nonclassical pemphigus with exclusively IgG anti-desmocollin 3-specific antibodies., PMID:30671942
Pemphigus herpetiformis with autoantibodies to desmocollins 1, 2 and 3., PMID:29333762
Pathogenic IgG4 autoantibodies from endemic pemphigus foliaceus recognize a desmoglein-1 conformational epitope., PMID:29307589
Desmocollin 1 is abundantly expressed in atherosclerosis and impairs high-density lipoprotein biogenesis., PMID:29106519
Routine detection of serum antidesmocollin autoantibodies is only useful in patients with atypical pemphigus., PMID:28815795
Establishment of IgA ELISAs of mammalian recombinant proteins of human desmocollins 1-3., PMID:27150020
A Case of Pemphigus Herpetiformis with Only Immunoglobulin G Anti-Desmocollin 3 Antibodies., PMID:26848227
Clinical and immunological findings in 104 cases of paraneoplastic pemphigus., PMID:26358412
Anti-desmocollin autoantibodies in nonclassical pemphigus., PMID:25640111
Desmocollin-specific antibodies in a patient with Hailey-Hailey disease., PMID:25580559
Pemphigus herpetiformis with IgG autoantibodies to desmoglein 1 and desmocollin 1., PMID:25244249
Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma., PMID:24980095
IgA/IgG pemphigus with infiltration of neutrophils and eosinophils in an ulcerative colitis patient., PMID:24604005
Two cases of pemphigus vegetans with IgG anti-desmocollin 3 antibodies., PMID:23946009
IgA paraneoplastic pemphigus in angioimmunoblastic T-cell lymphoma with antibodies to desmocollin 1, type VII collagen and laminin 332., PMID:23824361
IgA pemphigus with non-pustular erythematous lesions and IgA antibodies to desmocollins 1 and 2., PMID:23797684
Coexistence of pemphigus herpetiformis with IgG antibodies to desmocollin 1 and pemphigoid with IgG antibodies to BP180 C-terminal domain and laminin γ2., PMID:23715433
Regulation and impairments of dynamic desmosome and corneodesmosome remodeling., PMID:23644578
IgA pemphigus with paraneoplastic pemphigus-like clinical features showing IgA antibodies to desmoglein 1/3 and desmocollin 3, and IgG and IgA antibodies to the basement membrane zone., PMID:23517469
Pemphigus vulgaris autoantibody profiling by proteomic technique., PMID:23505434
New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease., PMID:23257250
Cloning and establishment of canine desmocollin-1 as a major autoantigen in canine pemphigus foliaceus., PMID:22884397
Etanercept restores a differentiated keratinocyte phenotype in psoriatic human skin: a morphological study., PMID:22716254
Loss of correlation between intensities of desmoglein 2 and desmoglein 3 expression in basal cell carcinomas., PMID:21933638
IgA pemphigus., PMID:21679872
IgA pemphigus and pustular psoriasis: a possible relation., PMID:21233060
Bullous dermatosis associated with IgG antibodies specific for desmocollins., PMID:20610368
IgA pemphigus reacting exclusively to desmoglein 3., PMID:20605770
Antidesmocollin-1 antibody-positive, antidesmoglein antibody-negative pemphigus herpetiformis., PMID:20542173
Autoantibodies against desmocollins in European patients with pemphigus., PMID:19456767
Intraepidermal neutrophilic IgA/IgG antidesmocollin 1 pemphigus., PMID:16634923
Early epidermal response after a single dose of gamma-rays in organotypic culture of human breast skin., PMID:16225595
Desmocollin 1 and desmoglein 1 expression in human epidermis and keratinizing oral mucosa: a comparative immunohistochemical and molecular study., PMID:15926049
Desmosome-binding antibody KM48 recognises an extracellular antigen different from desmosomal cadherins Dsg 1-3 and Dsc 1-3., PMID:15757816
Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion., PMID:15606501
The detection of IgG and IgA autoantibodies to desmocollins 1-3 by enzyme-linked immunosorbent assays using baculovirus-expressed proteins, in atypical pemphigus but not in typical pemphigus., PMID:15270874
Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7., PMID:15140227
Two Brazilian cases of IgA pemphigus., PMID:14739515
For research use only. Not for human or drug use.
