Catalog No.
PHE74001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD39/ENTPD1 (Met1-Tyr340).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen
Purification
Purified by antigen affinity column.
Accession
P49961
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Therapeutic potential of adenosine receptor modulators in cancer treatment., PMID:40530308
Frequency and stability of populations of CD4+ and CD4+CD25+Foxp3+CD127lo Treg in healthy adults defined by cytometry using monoclonal antibodies to T cell associated molecules., PMID:40464367
Assessment of CD73 activity in breast cancer-derived small extracellular vesicles: application to monitoring of patients' responses to immunotherapy., PMID:40390761
Identification and characterization of tissue resident memory T cells in malignant pleural effusions associated with non-small cell lung cancer., PMID:40285480
Adenosine-generating CD39+ plasmablasts predispose to successful infliximab therapy in pediatric IBD., PMID:40199584
Targeting Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer: Beyond PD-1/PD-L1 Monoclonal Antibodies., PMID:40075753
Complement Activation and Hemolysis in Non-Human Primates Following Transfusion of Genetically Modified Pig Red Blood Cells., PMID:39933991
Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma., PMID:39884778
Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma., PMID:39791721
Persistence of activated anti-mesothelin hYP218 chimeric antigen receptor T cells in the tumour is associated with efficacy in gastric and colorectal carcinomas., PMID:39548594
Perioperative sintilimab and neoadjuvant anlotinib plus chemotherapy for resectable non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 2 trial (TD-NeoFOUR trial)., PMID:39465257
Allogenic MSC infusion in kidney transplantation recipients promotes within 4 hours distinct B cell and T cell phenotypes., PMID:39450174
Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies., PMID:39431011
Effects of two immunosuppression regimens on T-lymphocyte subsets in elderly kidney transplant recipients., PMID:39372414
Single-arm trial of neoadjuvant ipilimumab plus nivolumab with chemoradiotherapy in patients with resectable and borderline resectable lung cancer: the INCREASE study., PMID:39349061
Mitigation of checkpoint inhibitor-induced autoimmune hemolytic anemia through modulation of purinergic signaling., PMID:39102659
The immune landscape of the inflamed joint defined by spectral flow cytometry., PMID:39101538
The reduced frequency of CD39+CD73+ B cell subsets in SLE patients is correlated with disease activity., PMID:39094356
Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study., PMID:38947379
ADA/CD26 axis increases intra-tumor PD-1+CD28+CD8+ T-cell fitness and affects NSCLC prognosis and response to ICB., PMID:38915783
Characterization of AB598, a CD39 Enzymatic Inhibitory Antibody for the Treatment of Solid Tumors., PMID:38797955
CD200R activation on naïve T cells by B cells induces suppressive activity of T cells via IL-24., PMID:38780647
Adjuvant Pembrolizumab in Patients with Stage IIIA/N2 Non-Small Cell Lung Cancer Completely Resected after Neoadjuvant Concurrent Chemoradiation: A Prospective, Open-Label, Single-Arm, Phase 2 Trial., PMID:38697848
Generation and characterization of antagonistic anti-human CD39 nanobodies., PMID:38590528
Magnetic CAR T cell purification using an anti-G4S linker antibody., PMID:38574803
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease., PMID:38552723
Regulatory T cell-derived exosome mediated macrophages polarization for osteogenic differentiation in fracture repair., PMID:38508525
Epitope Mapping of an Anti-Mouse CD39 Monoclonal Antibody Using PA Scanning and RIEDL Scanning., PMID:38507671
CD44 expression on murine hepatic stellate cells promotes the induction of monocytic and polymorphonuclear myeloid-derived suppressor cells., PMID:38484149
The aged microenvironment impairs BCL6 and CD40L induction in CD4+ T follicular helper cell differentiation., PMID:38481058
rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors., PMID:38471713
Efficacy and safety of autologous tumor-infiltrating lymphocytes in recurrent or refractory ovarian cancer, colorectal cancer, and pancreatic ductal adenocarcinoma., PMID:38309721
[Establishment of a 21-color Panel for the Detection of Immune Cell Subsets
in Human Non-small Cell Lung Cancer Tumor Tissues with Flow Cytometry]., PMID:38296626
In vitro B cell experiments explore the role of CD24, CD38, and energy metabolism in ME/CFS., PMID:38259473
Development of a Sensitive Anti-Mouse CD39 Monoclonal Antibody (C39Mab-1) for Flow Cytometry and Western Blot Analyses., PMID:38197855
[ARL67156, a small-molecule CD39 inhibitor, enhances natural killer cell cytotoxicity against gastric cancer cells in vitro and in nude mice]., PMID:38189385
A Rat Anti-Mouse CD39 Monoclonal Antibody for Flow Cytometry., PMID:38126892
Immune checkpoints are predominantly co-expressed by clonally expanded CD4+FoxP3+ intratumoral T-cells in primary human cancers., PMID:38057799
Leptin favors imbalance of antigen-specific CD4+ T-cells associated with severity of cat allergy., PMID:37954580
Exploring the Expression of Adenosine Pathway-Related Markers CD73 and CD39 in Colorectal and Pancreatic Carcinomas Characterized by Multiplex Immunofluorescence: A Pilot Study., PMID:37926083
Adenosine in cancer immunotherapy: Taking off on a new plane., PMID:37913941
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization., PMID:37749499
Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study., PMID:37700538
Proinflammatory allogeneic dendritic cells enhance the therapeutic efficacy of systemic anti-4-1BB treatment., PMID:37654492
Low Pretreatment CD4+:CD8+ T Cell Ratios and CD39+CD73+CD19+ B Cell Proportions Are Associated with Improved Relapse-Free Survival in Head and Neck Squamous Cell Carcinoma., PMID:37628721
Relationship between the Gene Expression of Adenosine Kinase Isoforms and the Expression of CD39 and CD73 Ectonucleotidases in Colorectal Cancer., PMID:37538807
BMPRII+ neural precursor cells isolated and characterized from organotypic neurospheres: an in vitro model of human fetal spinal cord development., PMID:37488910
Inhibitors of the CD73-adenosinergic checkpoint as promising combinatory agents for conventional and advanced cancer immunotherapy., PMID:37435071
Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment., PMID:37345056
Advances in CD73 inhibitors for immunotherapy: Antibodies, synthetic small molecule compounds, and natural compounds., PMID:37302340
For research use only. Not for human or drug use.
