Catalog No.
PHC81701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TXN (Val2-Val105).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Trx, TXN, TRX1, SASP, Hom s Trx, Thioredoxin, ATL-derived factor, ADF, TRX, Surface-associated sulphydryl protein, TRDX
Purification
Purified by antigen affinity column.
Accession
P10599
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Application of Indirect ELISA and PCR Techniques for Detecting of Hepatocellular Carcinoma using Des-gamma Carboxyprothrombin, Alpha-fetoprotein, and Thioredoxin Biomarkers., PMID:39998774
Biochemical, molecular and cytological impacts of alpha-lipoic acid and Ginkgo biloba in ameliorating testicular dysfunctions induced by silver nanoparticles in rats., PMID:35067888
Immunogenicity and protective response induced by recombinant Brucella abortus proteins Adk, SecB and combination of these two recombinant proteins against a virulent strain B. abortus 544 infection in BALB/c mice., PMID:32169487
The circadian clock protects against ferroptosis-induced sterile inflammation., PMID:32115146
Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy., PMID:31443184
Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody-Drug Conjugates., PMID:31085544
Inhibition of the thioredoxin system by PX-12 (1-methylpropyl 2-imidazolyl disulfide) impedes HIV-1 infection in TZM-bl cells., PMID:30948772
β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor., PMID:30100908
The Role of Redox-Regulating Enzymes in Inoperable Breast Cancers Treated with Neoadjuvant Chemotherapy., PMID:29348788
Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in a porcine model of donation after cardiac death., PMID:29087049
Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress., PMID:28224212
Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: IMPLICATIONS FOR CELIAC DISEASE., PMID:28003361
Screening for potential serum biomarkers in rat mesangial proliferative nephritis., PMID:26791873
Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells., PMID:26094816
[Cloning and expression and preliminary antigenicity identification for the diagnostic antigen of hepatitis E virus]., PMID:25975408
Integrative quantitative proteomics unveils proteostasis imbalance in human hepatocellular carcinoma developed on nonfibrotic livers., PMID:25225353
Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization., PMID:24376827
Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA., PMID:24130874
In vitro and in vivo activities of recombinant anthrax protective antigen co-expressed with thioredoxin in Escherichia coli., PMID:23880942
Functional analyses of complement convertases using C3 and C5-depleted sera., PMID:23071769
A protein disulfide isomerase/thioredoxin-1 complex is physically attached to exofacial membrane tumor necrosis factor receptors: overexpression in chronic lymphocytic leukemia cells., PMID:22775451
Determination and control of low-level amino acid misincorporation in human thioredoxin protein produced in a recombinant Escherichia coli production system., PMID:22334292
Discovery of ATL: an odyssey in restrospect., PMID:22068231
[Preparation of polyclonal antibody of recombinant human thioredoxin-1 and its protective effects on neonatal rats with endotoxemia]., PMID:22000444
Expression of redox pathway enzymes in human prostatic tissue., PMID:20698352
Auto- and cross-reactivity to thioredoxin allergens in allergic bronchopulmonary aspergillosis., PMID:19032234
Preparation and identification of monoclonal antibodies against recombinant human thioredoxins., PMID:17979552
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1., PMID:17557078
Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production., PMID:17030181
Thioredoxin-1 ameliorates myosin-induced autoimmune myocarditis by suppressing chemokine expressions and leukocyte chemotaxis in mice., PMID:15337697
Purification and characterization of delta3Trx-1, a splicing variant of human thioredoxin-1 lacking exon 3., PMID:12597892
Evidence for a trypanothione-dependent peroxidase system in Trypanosoma cruzi., PMID:10754272
Evaluation of single- and dual antigen delayed fluorescence immunoassay in comparison to an ELISA and the in vivo toxin neutralisation test for detection of diphtheria toxin antibodies., PMID:10594360
p53 immunohistochemical and genetic alterations are associated at high incidence with post-irradiated locally persistent prostate carcinoma., PMID:8627854
Cellular proliferative fraction of metastatic lymph nodes predicts survival in stage D1 (TxN+M0) prostate cancer., PMID:8627851
For research use only. Not for human or drug use.
