Anti-CAPN3 Polyclonal Antibody

Catalog No.

PHD42101

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CAPN3 (Ile602-Ala821).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CANPL3, New calpain 1, nCL-1, Calpain p94, Calpain L3, CANP3, CAPN3, Calcium-activated neutral proteinase 3, Muscle-specific calcium-activated neutral protease 3, Calpain-3, NCL1, CANP 3

Purification

Purified by antigen affinity column.

Accession

P20807

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

In situ detection of activation of CAPN3, a responsible gene product for LGMDR1, in mouse skeletal myotubes., PMID:40280419

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP-activated protein kinase signalling and poor exercise tolerance in a model of limb-girdle muscular dystrophy R1/2A., PMID:33460149

Novel Missense CAPN3 Mutation Responsible for Adult-Onset Limb Girdle Muscular Dystrophy with Calves Hypertrophy., PMID:31410652

Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function., PMID:28915917

Expression and localization of calpain 3 in the submandibular gland of mice., PMID:27295390

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness., PMID:24126726

Analysis of calpain-3 protein in muscle biopsies of different muscular dystrophies from India., PMID:22825607

Immunodetection analysis of muscular dystrophies in Mexico., PMID:22334167

Reverse protein arrays as novel approach for protein quantification in muscular dystrophies., PMID:20304647

Immunohistochemical analysis of calpain 3: advantages and limitations in diagnosing LGMD2A., PMID:19556129

Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis., PMID:19291799

Analysis of the UK diagnostic strategy for limb girdle muscular dystrophy 2A., PMID:18055493

Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain., PMID:17371879

Analysis of histopathologic and molecular pathologic findings in Czech LGMD2A patients., PMID:16372320

Protein studies in dysferlinopathy patients using llama-derived antibody fragments selected by phage display., PMID:15827562

Localization of calpain 3 in human skeletal muscle and its alteration in limb-girdle muscular dystrophy 2A muscle., PMID:12801918

Calpain 3 is expressed in astrocytes of rat and Microcebus brain., PMID:12663060

[Recent advances in limb-girdle muscular dystrophy research]., PMID:12235836

[A case of LGMD2A identified with both western blot analysis and immunostaining of calpain 3 in biopsied muscle]., PMID:11296367

Calpain-3 and dysferlin protein screening in patients with limb-girdle dystrophy and myopathy., PMID:11245721

Multiplex Western blotting system for the analysis of muscular dystrophy proteins., PMID:10233840

Purification and identification of two putative autolytic sites in human calpain 3 (p94) expressed in heterologous systems., PMID:10068445

Characterization of monoclonal antibodies to calpain 3 and protein expression in muscle from patients with limb-girdle muscular dystrophy type 2A., PMID:9777948

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