Catalog No.
PHE64801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DHPS (Met1-Asp369).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:500-1:4000
Target
DHPS, Deoxyhypusine synthase, DHS, DS
Concentration
0.6 mg/ml
Purification
Purified by antigen affinity column.
Accession
P49366
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
High-fidelity in silico generation and augmentation of TCR repertoire data using generative adversarial networks., PMID:40419551
Development of a reliable, sensitive, and convenient assay for the discovery of new eIF5A hypusination inhibitors., PMID:39937781
Novel deoxyhypusine synthase (DHPS) inhibitors target hypusination-induced vasculogenic mimicry (VM) against malignant melanoma., PMID:39393437
DHPS-Mediated Hypusination Regulates METTL3 Self-m6A-Methylation Modification to Promote Melanoma Proliferation and the Development of Novel Inhibitors., PMID:38952061
Sustained clinical benefit of malaria chemoprevention with sulfadoxine-pyrimethamine (SP) in pregnant women in a region with high SP resistance markers., PMID:38574776
Dihydropteroate synthase based sensor for screening multi-sulfonamides residue and its comparison with broad-specific antibody based immunoassay by molecular modeling analysis., PMID:30661581
Class-Specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays Used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity., PMID:30580515
Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes., PMID:28883613
A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity., PMID:28222187
A highly sensitive and class-specific fluorescence polarisation assay for sulphonamides based on dihydropteroate synthase., PMID:25775967
Isolation and characterization of Toxoplasma gondii genotypes from goats at an abattoir in Okinawa., PMID:22446126
Efficacy of the fibroblast growth factor inhibitor 2,5-dihydroxyphenylsulfonate in basal cell carcinoma: a histopathological and inmunohistochemical study., PMID:21756148
Hemoperfusion treatment in a septic shock patient with autosomal dominant polycystic kidney disease and increased HMGB1 protein levels., PMID:21654166
Dihydropteroate synthase (DHPS) gene mutation study in HIV-Infected Indian patients with Pneumocystis jirovecii pneumonia., PMID:21252456
Enhanced excitation-coupled Ca(2+) entry induces nuclear translocation of NFAT and contributes to IL-6 release from myotubes from patients with central core disease., PMID:21088110
Study of dihydropteroate synthase (DHPS) gene mutations among isolates of Pneumocystis jiroveci., PMID:19246797
[Obtaining antibodies to 1,4-dihydropyridine calcium channel blockers]., PMID:18663964
Prevalence of DHPS polymorphisms associated with sulfa resistance in South African Pneumocystis jirovecii strains., PMID:17169020
Pneumocystosis: survey and DHPS genotype analysis in 14 Parisian hospitals in 2003 and 2004., PMID:17169018
Nifedipine inhibits tumor necrosis factor-alpha-induced upregulation of monocyte chemoattractant protein-1 mRNA levels by suppressing CD40 expression in endothelial cells., PMID:15921025
Engineering dihydropteroate synthase (DHPS) for efficient expression on M13 phage., PMID:15894428
Prevention of experimental diffuse lamellar keratitis using a novel platelet-activating factor receptor antagonist., PMID:15093656
Disruption of intestinal motility by a calcium channel-stimulating autoantibody in type 1 diabetes., PMID:14988836
Development of an enzyme immunoassay for serum 16-dehydropregnenolone., PMID:11510475
Photoaffinity labeling and purification of ZG-16p, a high-affinity dihydropyridine binding protein of rat pancreatic zymogen granule membranes that regulates a K(+)-selective conductance., PMID:10648640
Effects of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes., PMID:10377955
Effect of cerebrocrast on the lymphocyte blast transformation activity in normal and streptozotocin-induced diabetic rats., PMID:10377954
Regional expression and functional characterization of the L-type Ca2+-channel in myocardium from patients with end-stage heart failure and in non-failing human hearts., PMID:10072735
Passive transfer of Lambert-Eaton myasthenic syndrome induces dihydropyridine sensitivity of ICa in mouse motor nerve terminals., PMID:9744921
Alternative splicing of exons in the alpha1 subunit of the rat testis L-type voltage-dependent calcium channel generates germ line-specific dihydropyridine binding sites., PMID:9570267
Epitope characterization of malondialdehyde-acetaldehyde adducts using an enzyme-linked immunosorbent assay., PMID:9305579
Conditional differentiation of heart- and smooth muscle-derived cells transformed by a temperature-sensitive mutant of SV40 T antigen., PMID:8838663
Expression of calcium channel subunits in the normal and diseased human myocardium., PMID:8820405
Antisense depletion of beta-subunits modulates the biophysical and pharmacological properties of neuronal calcium channels., PMID:7537818
Temporal differences in the induction of dihydropyridine receptor subunits and ryanodine receptors during skeletal muscle development., PMID:8063821
Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum., PMID:8041761
Co-localization of 1,4-dihydropyridine receptor alpha 2/delta subunit and N-CAM during early myogenesis in vitro., PMID:7929631
Immunohistochemical localization of L-type calcium channels in the developing first molar of the rat during odontoblast differentiation., PMID:8185503
Calcium channel subtypes controlling serotonin release from human small cell lung carcinoma cell lines., PMID:8253745
Phosphorylation of the L-type calcium channel beta subunit is involved in beta-adrenergic signal transduction in canine myocardium., PMID:8253200
G(o) transduces GABAB-receptor modulation of N-type calcium channels in cultured dorsal root ganglion neurons., PMID:8309795
Identification of 1,4-dihydropyridine binding domains within the primary structure of the alpha 1 subunit of the skeletal muscle L-type calcium channel., PMID:8405401
Purification of the cardiac 1,4-dihydropyridine receptor using immunoaffinity chromatography with a monoclonal antibody against the alpha 2 delta subunit of the skeletal muscle dihydropyridine receptor., PMID:1332871
1,4-Dihydropyridines modulate GTP hydrolysis by Go in neuronal membranes., PMID:1382024
Cyclic AMP-dependent phosphorylation and regulation of the cardiac dihydropyridine-sensitive Ca channel., PMID:1325377
Degradation of rat liver cytochromes P450 3A after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: characterization of the proteolytic system., PMID:1497342
Structural characterization of the dihydropyridine receptor-linked calcium channel from porcine heart., PMID:1328169
Expression of dihydropyridine-sensitive brain calcium channels in the rat central nervous system., PMID:1312035
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart., PMID:1683272
Inducible bilirubin-degrading system of rat liver microsomes: role of cytochrome P450IA1., PMID:1944239