Catalog No.
VVV22002
Species reactivity
Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Envelope glycoprotein B, gB, BALF4, gB, EBVaGC1_061
Concentration
1.35 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
R4R670
Applications
Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0134
Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases. PMID: 34691042
Protective anti-gB neutralizing antibodies targeting two vulnerable sites for EBV-cell membrane fusion. PMID: 35917353
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. PMID: 29292383
The COMPLEXity in herpesvirus entry. PMID: 28538165
Mapping regions of Epstein-Barr virus (EBV) glycoprotein B (gB) important for fusion function with gH/gL. PMID: 21376360
HCMV gB shares structural and functional properties with gB proteins from other herpesviruses. PMID: 23089254
Metastatic disease in head & neck oncology. PMID: 32469009
gH/gL supercomplexes at early stages of herpesvirus entry. PMID: 26849495
Glycoprotein B Antibodies Completely Neutralize EBV Infection of B Cells. PMID: 35711430
Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome. PMID: 27501260
Vesicular Stomatitis Virus-Based Epstein-Barr Virus Vaccines Elicit Strong Protective Immune Responses. PMID: 35404082
Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus. PMID: 27094060
Modulation of Epstein-Barr virus glycoprotein B (gB) fusion activity by the gB cytoplasmic tail domain. PMID: 23341550
Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. PMID: 17655906
Stuck in the middle: structural insights into the role of the gH/gL heterodimer in herpesvirus entry. PMID: 23107819
Epstein-Barr Virus Fusion with Epithelial Cells Triggered by gB Is Restricted by a gL Glycosylation Site. PMID: 28956769
Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion. PMID: 19457993
Potential entry receptors for human γ-herpesvirus into epithelial cells: A plausible therapeutic target for viral infections. PMID: 34800753
Integrins as triggers of Epstein-Barr virus fusion and epithelial cell infection. PMID: 21178476
Epstein-Barr virus glycoprotein gB and gHgL can mediate fusion and entry in trans, and heat can act as a partial surrogate for gHgL and trigger a conformational change in gB. PMID: 25142593
Characterization of murine gammaherpesvirus 68 glycoprotein B (gB) homolog: similarity to Epstein-Barr virus gB (gp110). PMID: 8083987
Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. PMID: 28939750
The fusion loops and membrane proximal region of Epstein-Barr virus glycoprotein B (gB) can function in the context of herpes simplex virus 1 gB when substituted individually but not in combination. PMID: 23089849
Failure to complement infectivity of EBV and HSV-1 glycoprotein B (gB) deletion mutants with gBs from different human herpesvirus subfamilies. PMID: 9344919
Rabbits immunized with Epstein-Barr virus gH/gL or gB recombinant proteins elicit higher serum virus neutralizing activity than gp350. PMID: 27291087
Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B. PMID: 19196955
Analysis of Epstein-Barr virus glycoprotein B functional domains via linker insertion mutagenesis. PMID: 18987135
Epstein-Barr virus activates F-box protein FBXO2 to limit viral infectivity by targeting glycoprotein B for degradation. PMID: 30052682
Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice. PMID: 27926486
Predictors of Epstein-Barr virus serostatus in young people in England. PMID: 31779585
Epstein-Barr virus glycoprotein homologous to herpes simplex virus gB. PMID: 3027378
Cleavage of Epstein-Barr virus glycoprotein B is required for full function in cell-cell fusion with both epithelial and B cells. PMID: 19218203
HLA-DR and HLA-DP restricted epitopes from human cytomegalovirus glycoprotein B recognized by CD4+ T-cell clones from chronically infected individuals. PMID: 22797815
[The entry of Epstein-Barr virus into B lymphocytes and epithelial cells during infection]. PMID: 25272606
Four Decades of Prophylactic EBV Vaccine Research: A Systematic Review and Historical Perspective. PMID: 35493498
Glycoprotein B of bovine herpesvirus type 4: its phylogenetic relationship to gB equivalents of the herpesviruses. PMID: 7871762
Rapid Generation of TCR and CD8αβ Transgenic Virus Specific T Cells for Immunotherapy of Leukemia. PMID: 35572604
Robust Benchmark Structural Variant Calls of An Asian Using State-of-the-art Long-read Sequencing Technologies. PMID: 33662625
The Epstein-Barr virus (EBV) glycoprotein B cytoplasmic C-terminal tail domain regulates the energy requirement for EBV-induced membrane fusion. PMID: 25100836
Human Cytomegalovirus and Epstein-Barr virus specific immunity in patients with ulcerative colitis. PMID: 33772380
Human Cytomegalovirus and Epstein-Barr Virus Genotypes in Apical Periodontitis Lesions. PMID: 26435468
Proteins of purified Epstein-Barr virus. PMID: 15534216
Functional cross-reactivity between the glycoprotein B of herpes simplex virus type 1 and Epstein-Barr virus. PMID: 15493256
Multiple Sclerosis Pathogenesis: Possible Interplay between Vitamin D Status and Epstein Barr Virus Infection. PMID: 36722238
For research use only. Not for human or drug use.
