Catalog No.
RXX00201
Expression system
Mammalian Cells
Species reactivity
Clostridioides difficile (Peptoclostridium difficile)
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
Toxin A, 3.4.22.-, Glucosyltransferase TcdA, 2.4.1.-, tcdA, toxA, Clostridium difficile Toxin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P16154
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0993
Structural insight into recognition of Clostridioides difficile toxin A by novel neutralizing nanobodies targeting QTIN-like motifs within its receptor-binding domain., PMID:39577542
A fine-tuned yeast surface-display/secretion platform enables the rapid discovery of neutralizing antibodies against Clostridioides difficile toxins., PMID:37749574
Corrigendum: Structure-guided design of a potent Clostridioides difficile toxin A inhibitor., PMID:37065148
Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies., PMID:36466927
Facile Affinity Maturation of Single-Domain Antibodies Using Next-Generation DNA Sequencing., PMID:35157277
Application of Assisted Design of Antibody and Protein Therapeutics (ADAPT) improves efficacy of a Clostridium difficile toxin A single-domain antibody., PMID:29396522
Intravenous adenovirus expressing a multi-specific, single-domain antibody neutralizing TcdA and TcdB protects mice from Clostridium difficile infection., PMID:27502696
Single domain antibody coated gold nanoparticles as enhancer for Clostridium difficile toxin detection by electrochemical impedance immunosensors., PMID:25460611
A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice., PMID:24683195
Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile., PMID:24311789
Engineered single-domain antibodies with high protease resistance and thermal stability., PMID:22140551
Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain., PMID:21216961
Toxin-specific antibodies for the treatment of Clostridium difficile: current status and future perspectives., PMID:22069622
For research use only. Not for human or drug use.
