Catalog No.
RVV19301
Expression system
Mammalian Cells
Species reactivity
Human immunodeficiency virus 1
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
Gag polyprotein, Matrix protein p17, MA, gag
Concentration
0.37 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
B6DRA0
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0889
HIV Gag polyprotein: processing and early viral particle assembly. PMID: 23266279
Relationship between HIV-1 Gag Multimerization and Membrane Binding. PMID: 35337029
The Life-Cycle of the HIV-1 Gag-RNA Complex. PMID: 27626439
Budding of a Retrovirus: Some Assemblies Required. PMID: 33092109
The HIV-1 Gag Protein Displays Extensive Functional and Structural Roles in Virus Replication and Infectivity. PMID: 35886917
Recent Advances in HIV-1 Gag Inhibitor Design and Development. PMID: 32272714
How HIV-1 Gag Manipulates Its Host Cell Proteins: A Focus on Interactors of the Nucleocapsid Domain. PMID: 32823718
HIV-1 Packaging Visualised by In-Gel SHAPE. PMID: 34960658
Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and the basic region of matrix protein. PMID: 10482606
Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein. PMID: 22348230
The molecular architecture of HIV. PMID: 21762795
Dynamic interactions of the Gag polyprotein. PMID: 8791725
HIV-1 assembly, budding, and maturation. PMID: 22762019
The structural biology of HIV assembly. PMID: 18406133
Distinct Contributions of Different Domains within the HIV-1 Gag Polyprotein to Specific and Nonspecific Interactions with RNA. PMID: 32252233
Dynamics of HIV-1 Gag Processing as Revealed by Fluorescence Lifetime Imaging Microscopy and Single Virus Tracking. PMID: 35215933
Integrative structural biology of HIV-1 capsid protein assemblies: combining experiment and computation. PMID: 33901736
New insights into HIV assembly and trafficking. PMID: 21841072
Modeling the full length HIV-1 Gag polyprotein reveals the role of its p6 subunit in viral maturation and the effect of non-cleavage site mutations in protease drug resistance. PMID: 29237328
CryoET structures of immature HIV Gag reveal six-helix bundle. PMID: 33863979
Human immunodeficiency virus type 1 Gag polyprotein modulates its own translation. PMID: 17041220
Rendezvous at Plasma Membrane: Cellular Lipids and tRNA Set up Sites of HIV-1 Particle Assembly and Incorporation of Host Transmembrane Proteins. PMID: 32752131
[Membrane Binding of Retroviral Gag Proteins]. PMID: 26437838
Functional domains of HIV-1 gag-polyprotein expressed in baculovirus-infected cells. PMID: 1871977
The role of matrix in HIV-1 envelope glycoprotein incorporation. PMID: 24933691
Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2. PMID: 11087859
Biochemical Reconstitution of HIV-1 Assembly and Maturation. PMID: 31801870
Overview of the Nucleic-Acid Binding Properties of the HIV-1 Nucleocapsid Protein in Its Different Maturation States. PMID: 33003650
The tRNALys packaging complex in HIV-1. PMID: 15183344
Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease. PMID: 2692658
[HIV-1 biogenesis unmasked]. PMID: 19038087
Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization. PMID: 8676452
Essential and supporting host cell factors for HIV-1 budding. PMID: 22004035
Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling. PMID: 27515235
HIV-1 assembly and maturation. PMID: 15168195
The HIV-1 assembly machine. PMID: 11816161
Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy. PMID: 25713345
Role of HIV-1 Gag domains in viral assembly. PMID: 12873766
The nucleic acid chaperone activity of the HIV-1 Gag polyprotein is boosted by its cellular partner RPL7: a kinetic study. PMID: 32797159
Characterization of a myristoylated, monomeric HIV Gag protein. PMID: 19285328
HIV-1 sequences isolated from patients promote expression of shorter isoforms of the Gag polyprotein. PMID: 27659676
Mutational analysis of HIV-1 gag proteins (review). PMID: 10934287
Incorporation of Pr160(gag-pol) into virus particles requires the presence of both the major homology region and adjacent C-terminal capsid sequences within the Gag-Pol polyprotein. PMID: 9151838
NC-mediated nucleolar localization of retroviral gag proteins. PMID: 23036987
HIV-1 gag proteins: diverse functions in the virus life cycle. PMID: 9813197