Plugging gp120s cavity. PMID: 19000812
Progress in targeting HIV-1 entry. PMID: 16182193
HIV-1--co-receptors binding. PMID: 9095160
Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion. PMID: 21647388
Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug. PMID: 21345545
HIV-1 gp120: A Target for Therapeutics and Vaccine Design. PMID: 26302793
Interaction of the HIV-1 gp120 viral protein V3 loop with bacterial lipopolysaccharide: a pattern recognition inhibition. PMID: 21636577
Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways. PMID: 12960231
Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity. PMID: 28446609
GP120: target for neutralizing HIV-1 antibodies. PMID: 16551265
CD4 activation of HIV fusion. PMID: 1281202
Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120. PMID: 29463753
The C4 region as a target for HIV entry inhibitors--NMR mapping of the interacting segments of T20 and gp120. PMID: 26432362
Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41. PMID: 26324044
Conformational properties of HIV-1 gp120/V3 immunogenic domains. PMID: 15974987
HIV-1 attachment: another look. PMID: 10217828
Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor. PMID: 34372601
Cell surface down-modulation of CD4 after infection by HIV-1. PMID: 8005387
[Sequence variation of HIV and bioinformatics]. PMID: 15449902
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. PMID: 15591114
Structure and Dynamics of the Native HIV-1 Env Trimer. PMID: 25762739
Multiple binding modes of an N-terminal CCR5-peptide in complex with HIV-1 gp120. PMID: 34921512
HIV-1 gp120 and immune network. PMID: 15370273
Mechanisms of apoptosis induction by the HIV-1 envelope. PMID: 15719026
HIV-1 entry and its inhibition. PMID: 12932074
Gp120 binding with DC-SIGN induces reactivation of HIV-1 provirus via the NF-κB signaling pathway. PMID: 26837416
HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors. PMID: 12873765
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. PMID: 24502450
Sequence-conserved and antibody-accessible sites in the V1V2 domain of HIV-1 gp120 envelope protein. PMID: 25051095
Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface. PMID: 34586861
Stoichiometric parameters of HIV-1 entry. PMID: 25463598
Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy. PMID: 24801282
The HIV-1 Env protein signal sequence retards its cleavage and down-regulates the glycoprotein folding. PMID: 10873786
Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin. PMID: 9213396
Glycosylation of the ENV spike of primate immunodeficiency viruses and antibody neutralization. PMID: 15279588
Effect of HIV-1 Env on SERINC5 Antagonism. PMID: 27928004
The HIV-inactivating protein, cyanovirin-N, does not block gp120-mediated virus-to-cell binding. PMID: 9704015
Redox control on the cell surface: implications for HIV-1 entry. PMID: 12626125
Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint. PMID: 34469718
The SPL7013 dendrimer destabilizes the HIV-1 gp120-CD4 complex. PMID: 26495445
Caprine arthritis-encephalitis virus envelope surface glycoprotein regions interacting with the transmembrane glycoprotein: structural and functional parallels with human immunodeficiency virus type 1 gp120. PMID: 14557643
Virus entry as a target for anti-HIV intervention. PMID: 12871111
Probability of Immobilization on Host Cell Surface Regulates Viral Infectivity. PMID: 33016741
Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies. PMID: 2234433
Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity. PMID: 23297802
Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate. PMID: 33057580
Assays to detect and characterize human immunodeficiency virus type 1 (HIV-1) receptor antagonists, compounds that inhibit binding of the HIV-1 surface glycoprotein, gp120, to the CD4 receptor on human T lymphocytes. PMID: 7811011
HbAHP-25 attenuates HIV-1 gp120 mediated inflammation and barrier dysfunction. PMID: 29210152
HIV-1 entry inhibitors in the side pocket. PMID: 10555140
Coreceptors: implications for HIV pathogenesis and therapy. PMID: 9122710
From receptor recognition mechanisms to bioinspired mimetic antagonists in HIV-1/cell docking. PMID: 11334348
Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120. PMID: 20016882
gp120: Biologic aspects of structural features. PMID: 11244037
The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel. PMID: 26018158
A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. PMID: 20527993
Inhibition of HIV entry by carbohydrate-binding proteins. PMID: 16569440
Allosteric induction of the CD4-bound conformation of HIV-1 Gp120. PMID: 24304511
HIV gp120: double lock strategy foils host defences. PMID: 9739096
An anti-HIV-1 gp120 antibody expressed as an endocytotic transmembrane protein mediates internalization of HIV-1. PMID: 14592761
Molecular architecture of native HIV-1 gp120 trimers. PMID: 18668044
Characteristics of HIV-1 gp120 glycoprotein binding to glycolipids. PMID: 8021969
A study of the coevolutionary patterns operating within the env gene of the HIV-1 group M subtypes. PMID: 17921487
Autophagy and CD4+ T lymphocyte destruction by HIV-1. PMID: 17012832
Novel therapies based on mechanisms of HIV-1 cell entry. PMID: 12773651
A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein. PMID: 23696718
Retrocyclin, an antiretroviral theta-defensin, is a lectin. PMID: 12707350
HIV requires multiple gp120 molecules for CD4-mediated infection. PMID: 2374593
The role of the viral glycoprotein in HIV-1 persistence. PMID: 10065629
Antibody neutralization of human immunodeficiency virus type 1 (HIV-1). PMID: 12739253
Imaging of HIV-1 envelope-induced virological synapse and signaling on synthetic lipid bilayers. PMID: 22433250
Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate. PMID: 25915761
The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion. PMID: 18237398
Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip. PMID: 33883222
Cell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 Envelope. PMID: 26085151
CCR5 structural plasticity shapes HIV-1 phenotypic properties. PMID: 30521629
Inhibitors of HIV infection via the cellular CD4 receptor. PMID: 16611063
The N-terminal 31 amino acids of human immunodeficiency virus type 1 envelope protein gp120 contain a potential gp41 contact site. PMID: 2016774
Characterization of V3 loop-binding protein(s) of Molt-4 and U937 cells. PMID: 7576912
Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop. PMID: 11907225
Filamin-A regulates actin-dependent clustering of HIV receptors. PMID: 17572668
[Structure and function of oligosaccharide chains of the envelope glycoprotein gp120 of human immunodeficiency virus type 1]. PMID: 1518160
Potent suppression of HIV-1 cell attachment by Kudzu root extract. PMID: 30236131
For research use only. Not for human or drug use.
