Catalog No.
RVV03102
Expression system
Mammalian Cells
Species reactivity
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41, env
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P04578
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0881
Plugging gp120s cavity. PMID: 19000812
Progress in targeting HIV-1 entry. PMID: 16182193
HIV-1--co-receptors binding. PMID: 9095160
Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion. PMID: 21647388
Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug. PMID: 21345545
HIV-1 gp120: A Target for Therapeutics and Vaccine Design. PMID: 26302793
Interaction of the HIV-1 gp120 viral protein V3 loop with bacterial lipopolysaccharide: a pattern recognition inhibition. PMID: 21636577
Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways. PMID: 12960231
Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity. PMID: 28446609
GP120: target for neutralizing HIV-1 antibodies. PMID: 16551265
CD4 activation of HIV fusion. PMID: 1281202
Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120. PMID: 29463753
The C4 region as a target for HIV entry inhibitors--NMR mapping of the interacting segments of T20 and gp120. PMID: 26432362
Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41. PMID: 26324044
Conformational properties of HIV-1 gp120/V3 immunogenic domains. PMID: 15974987
HIV-1 attachment: another look. PMID: 10217828
Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor. PMID: 34372601
Cell surface down-modulation of CD4 after infection by HIV-1. PMID: 8005387
[Sequence variation of HIV and bioinformatics]. PMID: 15449902
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. PMID: 15591114
Structure and Dynamics of the Native HIV-1 Env Trimer. PMID: 25762739
Multiple binding modes of an N-terminal CCR5-peptide in complex with HIV-1 gp120. PMID: 34921512
HIV-1 gp120 and immune network. PMID: 15370273
Mechanisms of apoptosis induction by the HIV-1 envelope. PMID: 15719026
HIV-1 entry and its inhibition. PMID: 12932074
Gp120 binding with DC-SIGN induces reactivation of HIV-1 provirus via the NF-κB signaling pathway. PMID: 26837416
HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors. PMID: 12873765
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. PMID: 24502450
Sequence-conserved and antibody-accessible sites in the V1V2 domain of HIV-1 gp120 envelope protein. PMID: 25051095
Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface. PMID: 34586861
Stoichiometric parameters of HIV-1 entry. PMID: 25463598
Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy. PMID: 24801282
The HIV-1 Env protein signal sequence retards its cleavage and down-regulates the glycoprotein folding. PMID: 10873786
Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin. PMID: 9213396
Glycosylation of the ENV spike of primate immunodeficiency viruses and antibody neutralization. PMID: 15279588
Effect of HIV-1 Env on SERINC5 Antagonism. PMID: 27928004
The HIV-inactivating protein, cyanovirin-N, does not block gp120-mediated virus-to-cell binding. PMID: 9704015
Redox control on the cell surface: implications for HIV-1 entry. PMID: 12626125
Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint. PMID: 34469718
The SPL7013 dendrimer destabilizes the HIV-1 gp120-CD4 complex. PMID: 26495445
Caprine arthritis-encephalitis virus envelope surface glycoprotein regions interacting with the transmembrane glycoprotein: structural and functional parallels with human immunodeficiency virus type 1 gp120. PMID: 14557643
Virus entry as a target for anti-HIV intervention. PMID: 12871111
Probability of Immobilization on Host Cell Surface Regulates Viral Infectivity. PMID: 33016741
Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies. PMID: 2234433
Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity. PMID: 23297802
Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate. PMID: 33057580
Assays to detect and characterize human immunodeficiency virus type 1 (HIV-1) receptor antagonists, compounds that inhibit binding of the HIV-1 surface glycoprotein, gp120, to the CD4 receptor on human T lymphocytes. PMID: 7811011
HbAHP-25 attenuates HIV-1 gp120 mediated inflammation and barrier dysfunction. PMID: 29210152
HIV-1 entry inhibitors in the side pocket. PMID: 10555140
Coreceptors: implications for HIV pathogenesis and therapy. PMID: 9122710
For research use only. Not for human or drug use.
