Catalog No.
PHD30901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ATF1 (Asp3-Gln213).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
cAMP-dependent transcription factor ATF-1,Protein TREB36,Activating transcription factor 1,Cyclic AMP-dependent transcription factor ATF-1,ATF1
Purification
Purified by antigen affinity column.
Accession
P18846
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Pluripotent stem cell marker deficiency in salivary mucoepidermoid carcinoma with relevance to molecular profiling: An experimental study., PMID:40478494
Expression, molecular mechanisms and therapeutic potentials of ATF1 in cancers., PMID:39580140
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma., PMID:36959380
An obstructive role of NK cells on metastatic growth of clear-cell sarcoma cells in a xenoplant murine model., PMID:33262889
Hyalinizing Clear Cell Carcinoma of the Lung: Case Report and Review of the Literature., PMID:28927164
Signaling effects of sodium hydrosulfide in healthy donor peripheral blood mononuclear cells., PMID:27543462
Non-classical testosterone signaling mediated through ZIP9 stimulates claudin expression and tight junction formation in Sertoli cells., PMID:27164415
Fibroblast and Epidermal Growth Factors Utilize Different Signaling Pathways to Induce Anchorage-independent Cell Transformation in JB6 Cl41 Mouse Skin Epidermal Cells., PMID:25337589
The regulation of the expression and activation of the essential ATF1 transcription factor in the mouse preimplantation embryo., PMID:24962037
Non-classical testosterone signaling is mediated by a G-protein-coupled receptor interacting with Gnα11., PMID:24631506
Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation., PMID:24031026
Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2., PMID:23988737
Gene expression analysis in human breast cancer associated blood vessels., PMID:23056178
Transcription factor proteomics: identification by a novel gel mobility shift-three-dimensional electrophoresis method coupled with southwestern blot and high-performance liquid chromatography-electrospray-mass spectrometry analysis., PMID:21880322
Cytokeratin 8/18 monoclonal antibody was dissimilar to anti-cytokeratin CAM 5.2.--a comment on: "Discovery of two novel EWSR1/ATF1 transcripts in four chimerical transcripts-expressing clear cell sarcoma and their quantitative evaluation, Experimental and Molecular Pathology 90(2): 194-200, April 2011"., PMID:21510931
Identification of the receptor tyrosine kinase c-Met and its ligand, hepatocyte growth factor, as therapeutic targets in clear cell sarcoma., PMID:20068147
The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo., PMID:19776387
CREB1/ATF1 activation in photoreceptor degeneration and protection., PMID:19643965
Cigarette smoke suppresses in vitro allergic activation of mouse mast cells., PMID:19260869
CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation., PMID:18227154
cAMP-responsive element-binding protein expression and regulation in the mouse preimplantation embryo., PMID:17965257
Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation., PMID:17962702
Activating transcription factor-1-mediated hepatocyte growth factor-induced down-regulation of thrombospondin-1 expression leads to thyroid cancer cell invasion., PMID:17409099
Clear cell sarcoma of tendons and aponeuroses: a review., PMID:17227118
Association of the t(12;22)(q13;q12) EWS/ATF1 rearrangement with polyphenotypic round cell sarcoma of bone: a case report., PMID:16327442
Regulation of gene expression in melanoma: new approaches for treatment., PMID:15523674
Construction and expression of intracellular anti-ATF-1 single chain Fv fragment: a modality to inhibit melanoma tumor growth and metastasis., PMID:15312676
Transcriptional regulation of the human UDP-galactose:ceramide galactosyltransferase (hCGT) gene expression: functional role of GC-box and CRE., PMID:15229398
The ErbB2/Neu/HER2 receptor is a new calmodulin-binding protein., PMID:15080792
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration., PMID:15066262
Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis., PMID:14593102
Minimal structural elements of an inhibitory anti-ATF1/CREB single-chain antibody fragment (scFv41.4)., PMID:12831531
Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells., PMID:12519783
Rap1 reverses transcriptional repression of TGF-beta type II receptor by a mechanism involving AP-1 in the human pancreatic cancer cell line, UK Pan-1., PMID:12447993
Regulatory motifs for CREB-binding protein and Nfe2l2 transcription factors in the upstream enhancer of the mitochondrial uncoupling protein 1 gene., PMID:12084707
Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene., PMID:12072203
ATF-1 mediates protease-activated receptor-1 but not receptor tyrosine kinase-induced DNA synthesis in vascular smooth muscle cells., PMID:11925444
Targeting the ATF-1/CREB transcription factors by single chain Fv fragment in human melanoma: potential modality for cancer therapy., PMID:11642609
Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate., PMID:11354513
Preliminary X-ray diffraction studies of the transcriptional inhibitory antibody Fab41.4., PMID:11223533
Regulation of tyrosine hydroxylase gene transcription by the cAMP-signaling pathway: involvement of multiple transcription factors., PMID:11108136
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study., PMID:11074872
Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment., PMID:10851072
The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms., PMID:10812201
Activation of the c-fos enhancer by the erk MAP kinase pathway through two sequence elements: the c-fos AP-1 and p62TCF sites., PMID:10723128
Tumor cell viability in clear cell sarcoma requires DNA binding activity of the EWS/ATF1 fusion protein., PMID:10574952
The role of human MBF1 as a transcriptional coactivator., PMID:10567391
Serum responsiveness of the rat PCNA promoter involves the proximal ATF and AP-1 sites., PMID:9883884
Inhibition of activating transcription factor 1- and cAMP-responsive element-binding protein-activated transcription by an intracellular single chain Fv fragment., PMID:9642248
Developmental profiles of phosphorylated and unphosphorylated CREBs in murine calvarial MC3T3-E1 cells., PMID:9538221
For research use only. Not for human or drug use.
