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Anti-Human COL1A1 Nanobody (SAA1295)

Catalog #:   RHB97401 Specific References (50) DATASHEET
Host species: Alpaca
Isotype: VHH-8His-Cys-tag
Applications: ELISA
Expression system: Mammalian Cells
Overview

Catalog No.

RHB97401

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clonality

Monoclonal

Target

Collagen alpha-1(I) chain, COL1A1, Alpha-1 type I collagen

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P02452

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1295

Data Image
  • SDS-PAGE
    SDS PAGE for Human COL1A1 Nanobody
References

Mechanistic insights into Schisandrin C as the active anti-renal fibrosis ingredient of Schisandra chinensis: a network pharmacology analysis and transcriptomics integrated experimental verification., PMID:40500382

Anti-TGF-β treatment shows increased bone mass and strength in a novel mouse model for osteogenesis imperfecta type I., PMID:40358008

TSAb inhibits osteogenic differentiation of MC3T3-E1 cells and exacerbates bone loss in Graves' disease mice., PMID:40354515

Bone marrow mesenchymal stem cells alleviate liver fibrosis after rat liver transplantation through JAK1/STAT5 pathway., PMID:40312752

Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration., PMID:40111356

The effect of tocilizumab treatment for skin fibrosis by inhibiting CD38+ macrophages in systemic sclerosis., PMID:39778381

Osteogenesis imperfecta: shifting paradigms in pathophysiology and care in children., PMID:39670712

An anti-RAGE chimeric antibody alleviates CCl4-induced liver fibrosis via RAGE/NF-kB pathway in mice., PMID:39657505

Setrusumab for the treatment of osteogenesis imperfecta: 12-month results from the phase 2b asteroid study., PMID:39012717

Sclerostin antibody enhances implant osseointegration in bone with Col1a1 mutation., PMID:38876270

Galunisertib downregulates mutant type I collagen expression and promotes MSCs osteogenesis in pediatric osteogenesis imperfecta., PMID:38744219

Impact of tissue factor expression and administration routes on thrombosis development induced by mesenchymal stem/stromal cell infusions: re-evaluating the dogma., PMID:38414067

CETP-derived Peptide Seq-1, the Key Component of HB-ATV-8 Vaccine Prevents Stress Responses, and Promotes Downregulation of Pro-Fibrotic Genes in Hepatocytes and Stellate Cells., PMID:38301446

Platelets modulate cardiac remodeling via the collagen receptor GPVI after acute myocardial infarction., PMID:38274818

RIPK3 Expression in Fibroblasts in an in vivo and in vitro Skin Wound Model: A Controversial Result., PMID:38234604

Hepatocyte GPCR signaling regulates IRF3 to control hepatic stellate cell transdifferentiation., PMID:38233853

Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair., PMID:37978868

Bevacizumab promotes tenogenic differentiation and maturation of rat tendon-derived cells in vitro., PMID:37906574

Mesothelin expression remodeled the immune-matrix tumor microenvironment predicting the risk of death in patients with malignant pleural mesothelioma., PMID:37901248

Regulatory T-cell deficiency leads to features of autoimmune liver disease overlap syndrome in scurfy mice., PMID:37818371

Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial-mesenchymal transition in lung endothelial cells., PMID:37735673

[IgG78-DM1 inhibits pulmonary fibrosis by targeting and killing CD248-positive myofibroblasts in mice]., PMID:37732571

Identification of novel tumor-associated antigens and evaluation of a panel of autoantibodies in detecting oral cancer., PMID:37641028

Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation., PMID:37599332

Liver fibrotic development is reduced through inflammation prevention by an adenosine derivative compound., PMID:37544282

Whole-Body Metabolism and the Musculoskeletal Impacts of Targeting Activin A and Myostatin in Severe Osteogenesis Imperfecta., PMID:37457877

RNA-Seq Analysis of Peripheral Whole Blood from Dairy Bulls with High and Low Antibody-Mediated Immune Responses-A Preliminary Study., PMID:37444006

Histological and biochemical evaluation of the effects of silver nanoparticles (AgNps) versus titanium dioxide nanoparticles (TiO2NPs) on rat parotid gland., PMID:37132546

Drug suspending during wound healing effectively weakens immunosuppression-related complications by preserving CD8+ T cell function., PMID:37129099

Anti-scarring effects of conbercept on human Tenon's fibroblasts: comparisons with bevacizumab., PMID:37101202

Effect of sclerostin inactivation in a mouse model of severe dominant osteogenesis imperfecta., PMID:36973504

Identification of key genes in colorectal cancer diagnosis by co-expression analysis weighted gene co-expression network analysis., PMID:36931200

Individual immune cell and cytokine profiles determine platelet-rich plasma composition., PMID:36627721

Macular neovascularisation in a patient with osteogenesis imperfecta exhibiting a novel COL1A1 mutation., PMID:36343986

FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis., PMID:36087468

Glioblastoma-educated mesenchymal stem-like cells promote glioblastoma infiltration via extracellular matrix remodelling in the tumour microenvironment., PMID:35908277

ORF8 protein of SARS-CoV-2 reduces male fertility in mice., PMID:35570330

Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858

Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348

Abaloparatide Improves Rotator Cuff Healing via Anabolic Effects on Bone Remodeling in a Chronic Rotator Cuff Tear Model of Rat With Osteoporosis: A Comparison With Denosumab., PMID:35404150

Pathological differences in the bone healing processes between tooth extraction socket and femoral fracture., PMID:35372643

Circulating TGF-β Pathway in Osteogenesis Imperfecta Pediatric Patients Subjected to MSCs-Based Cell Therapy., PMID:35223854

Bevacizumab and sunitinib mediate osteogenic and pro-inflammatory molecular changes in primary human alveolar osteoblasts in vitro., PMID:35171372

Inhibitory effect of membrane‑free stem cell components derived from adipose tissues on skin inflammation in keratinocytes., PMID:35169867

Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome., PMID:35135328

Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis., PMID:35086525

Adhesion and proliferation properties of type I collagen-derived peptide for possible use in skin tissue engineering application., PMID:34882901

Migratory chondroprogenitors retain superior intrinsic chondrogenic potential for regenerative cartilage repair as compared to human fibronectin derived chondroprogenitors., PMID:34880351

Evaluation of cytokines in protective effect of docosahexaenoic acid in experimental achilles tendinopathy rat model induced with type-1 collagenase., PMID:34612118

The Wnt/β-catenin signaling pathway has a healing ability for periapical periodontitis., PMID:34608236

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human COL1A1 Nanobody (SAA1295) [RHB97401]
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