Anti-Human WNT1 Polyclonal Antibody

Catalog No.

PHC09701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human WNT1 (Gly32-Arg255).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

WNT1, Proto-oncogene Wnt-1, INT1, Proto-oncogene Int-1 homolog

Purification

Purified by antigen affinity column.

Accession

P04628

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Single-Cell Transcriptomics Identifies Selective Lineage-Specific Regulation of Genes in Aortic Smooth Muscle Cells in Mice., PMID:39744838

A mechanism of action-reflective, dual cell-based bioassay for determining the bioactivity of sclerostin-neutralizing antibodies., PMID:39389544

Dissociation of Drosophila Evi-Wg Complex Occurs Post Apical Internalization in the Maturing Acidic Endosomes., PMID:39313313

Relationship of posterior peripheral corneal layers and the trabecular meshwork: an immunohistological and anatomical study., PMID:38418206

Vitamin D improves autoimmune diseases by inhibiting Wnt signaling pathway., PMID:38414312

LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy., PMID:38388484

Porphyromonas gingivalis Lipopolysaccharide Damages Mucosal Barrier to Promote Gastritis-Associated Carcinogenesis., PMID:37943385

Wnt1 induces osteoblastic changes in a well-established osteolytic skeletal metastatic model derived from breast cancer., PMID:37840014

Multi-Targeting DKK1 and LRP6 Prevents Bone Loss and Improves Fracture Resistance in Multiple Myeloma., PMID:36987921

Genotypic and Phenotypic Spectrum and Pathogenesis of WNT1 Variants in a Large Cohort of Patients With OI/Osteoporosis., PMID:36595228

Optimal CCN4 Immunofluorescence for Tissue Microarray., PMID:36370340

Novel 2,6,9-Trisubstituted Purines as Potent CDK Inhibitors Alleviating Trastuzumab-Resistance of HER2-Positive Breast Cancers., PMID:36145262

R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer., PMID:36106661

A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis., PMID:35987202

WNT1-inducible signaling pathway protein 1 regulates kidney inflammation through the NF-κB pathway., PMID:34897418

A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation., PMID:34783308

7-Hydroxycoumarin mitigates the severity of collagen-induced arthritis in rats by inhibiting proliferation and inducing apoptosis of fibroblast-like synoviocytes via suppression of Wnt/β-catenin signaling pathway., PMID:34752968

Therapeutic DNA vaccine encoding CEMIP (KIAA1199) ameliorates kidney fibrosis in obesity through inhibiting the Wnt/β-catenin pathway., PMID:34582938

Inactivation of Wnt/β-catenin/renin angiotensin axis by tumor necrosis factor-alpha inhibitor, infliximab, ameliorates CKD induced in rats., PMID:33482150

E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling., PMID:33408116

Mechanical Ventilation with Moderate Tidal Volume Exacerbates Extrapulmonary Sepsis-Induced Lung Injury via IL33-WISP1 Signaling Pathway., PMID:33394970

18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis., PMID:33386938

Activity-dependent endocytosis of Wingless regulates synaptic plasticity in the Drosophila visual system., PMID:33298662

Acetazolamide ameliorates the severity of collagen-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting Wnt/β-catenin pathway., PMID:33278748

The expression and regulation of Wnt1 in tooth movement-initiated mechanotransduction., PMID:33139146

WNT1-inducible-signaling pathway protein 1 regulates the development of kidney fibrosis through the TGF-β1 pathway., PMID:32896021

The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases., PMID:32733380

Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancer., PMID:32537818

Wnt1/β-catenin signaling upregulates spinal VGLUT2 expression to control neuropathic pain in mice., PMID:31785260

WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy., PMID:31512238

Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers., PMID:31481760

Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action., PMID:31189118

Neuroprotection mediated by the Wnt/Frizzled signaling pathway in early brain injury induced by subarachnoid hemorrhage., PMID:30762013

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells., PMID:30664649

[Progressive pseudorheumatoid dysplasia misdiagnosed as ankylosing spondylitis: a case report]., PMID:30562792

WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice., PMID:30522479

Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment., PMID:30458886

RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade., PMID:30274786

Mechanism of fibrogenesis in submandibular glands in patients with IgG4-RD., PMID:30251185

Exploring pathways for sustained melanogenesis in facial melasma: an immunofluorescence study., PMID:29846953

Genomic Profile and Pathologic Features of Diffuse Large B-Cell Lymphoma Subtype of Methotrexate-associated Lymphoproliferative Disorder in Rheumatoid Arthritis Patients., PMID:29738359

Direct visualization of the Wntless-induced redistribution of WNT1 in developing chick embryos., PMID:29715461

LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells., PMID:29269400

Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells., PMID:29173982

Sox10+ Cells Contribute to Vascular Development in Multiple Organs-Brief Report., PMID:28751573

Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis., PMID:28628032

Ryk receptors on unmyelinated nerve fibers mediate excitatory synaptic transmission and CCL2 release during neuropathic pain induced by peripheral nerve injury., PMID:28565999

Wnt-1 immunodetection in the regenerating tail of lizard suggests it is involved in the proliferation and distal growth of the blastema., PMID:28233575

Progenitors in Peripheral Nerves Launch Heterotopic Ossification., PMID:28198109

Immunoexpression of Wnt/β-catenin signaling pathway proteins in ameloblastoma and calcifying cystic odontogenic tumor., PMID:28149478

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