Catalog No.
PHK74001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FLCN (Lys347-Asn579).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
BHD skin lesion fibrofolliculoma protein, FLCN, Birt-Hogg-Dube syndrome protein, BHD, Folliculin
Purification
Purified by antigen affinity column.
Accession
Q8NFG4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A case of severe allergic eosinophilic asthma with nasal polyposis in a patient affected by Birt-Hogg-Dubé syndrome successfully treated with benralizumab., PMID:34148334
Dominant atopy risk mutations identified by mouse forward genetic analysis., PMID:32810290
A case of Birt-Hogg-Dubé syndrome implying reduced or no wild-type folliculin without mutated protein is pathogenic., PMID:31778855
Smith-Magenis Syndrome Patients Often Display Antibody Deficiency but Not Other Immune Pathologies., PMID:28286158
Oncotargets in different renal cancer subtypes., PMID:25619751
Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases., PMID:24081491
Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN., PMID:23150719
Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product., PMID:19914239