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Anti-Human FLCN Polyclonal Antibody

Catalog #:   PHK74001 Specific References (8) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q8NFG4
Overview

Catalog No.

PHK74001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FLCN (Lys347-Asn579).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

BHD skin lesion fibrofolliculoma protein, FLCN, Birt-Hogg-Dube syndrome protein, BHD, Folliculin

Purification

Purified by antigen affinity column.

Accession

Q8NFG4

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with FLCN antibody (PHK74001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 28 kDa
    Observed MW: 28 kDa
References

A case of severe allergic eosinophilic asthma with nasal polyposis in a patient affected by Birt-Hogg-Dubé syndrome successfully treated with benralizumab., PMID:34148334

Dominant atopy risk mutations identified by mouse forward genetic analysis., PMID:32810290

A case of Birt-Hogg-Dubé syndrome implying reduced or no wild-type folliculin without mutated protein is pathogenic., PMID:31778855

Smith-Magenis Syndrome Patients Often Display Antibody Deficiency but Not Other Immune Pathologies., PMID:28286158

Oncotargets in different renal cancer subtypes., PMID:25619751

Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases., PMID:24081491

Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN., PMID:23150719

Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product., PMID:19914239

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-Human FLCN Polyclonal Antibody [PHK74001]
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