Catalog No.
PHD96401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DNAJA1 (Asn106-Asn327).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DnaJ protein homolog 2, DNAJA1, Heat shock protein J2, HDJ2, HSJ-2, HSJ2, HSPF4, Heat shock 40 kDa protein 4, HSDJ, DNAJ2, DnaJ homolog subfamily A member 1, Human DnaJ protein 2, hDj-2
Purification
Purified by antigen affinity column.
Accession
P31689
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Inhibition of mutant Kras and p53-driven pancreatic carcinogenesis by atorvastatin: Mainly via targeting of the farnesylated DNAJA1 in chaperoning mutant p53., PMID:31397499
Enhanced type I interferon gene signature in primary antiphospholipid syndrome: Association with earlier disease onset and preeclampsia., PMID:30772492
Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis., PMID:23408083
Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1., PMID:22085931
Farnesyltransferase inhibitors inhibit T-cell cytokine production at the posttranscriptional level., PMID:17545504
Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury., PMID:15299042
Overexpression of HDJ-2 protects astrocytes from ischemia-like injury and reduces redistribution of ubiquitin staining in vitro., PMID:14526221
Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia., PMID:11264179
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity., PMID:10942430
Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone., PMID:10196362
Characterization of HDJ-2, a human 40 kD heat shock protein., PMID:9839446
HSDJ, a human homolog of DnaJ, is farnesylated and is involved in protein import into mitochondria., PMID:9192730
Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein., PMID:8334160