Catalog No.
PHE92601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human AGFG1 (Met1-Thr151).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
AGFG1, Arf-GAP domain and FG repeat-containing protein 1, Rev/Rex activation domain-binding protein, Nucleoporin-like protein RIP, HIV-1 Rev-binding protein, Rev-interacting protein, RIP, HRB, RAB
Purification
Purified by antigen affinity column.
Accession
P52594
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2., PMID:38227684
Autophagy and Oncosis/Necroptosis Are Enhanced in Cardiomyocytes from Heart Failure Patients., PMID:30713336
TNF-α increases Staphylococcus aureus-induced death of human alveolar epithelial cell line A549 associated with RIP3-mediated necroptosis., PMID:29330116
Simultaneous flow cytometric immunophenotyping of necroptosis, apoptosis and RIP1-dependent apoptosis., PMID:29175336
Smac mimetics and type II interferon synergistically induce necroptosis in various cancer cell lines., PMID:28923396
RIP1 has a role in CD40-mediated apoptosis in human follicular lymphoma cells., PMID:28610909
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells., PMID:28498503
Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades., PMID:27847402
Smac mimetic sensitizes renal cell carcinoma cells to interferon-α-induced apoptosis., PMID:26912071
Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction., PMID:26729029
Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells., PMID:26575016
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling., PMID:26525107
CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells., PMID:26313915
Interferon-γ-induced necrosis: an antitumor biotherapeutic perspective., PMID:23570383
RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex., PMID:22890322
Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner., PMID:22469979
Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination., PMID:21613257
The involvement of β-actin in the signaling of transmembrane TNF-α-mediated cytotoxicity., PMID:21402772
Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex., PMID:19641134
Role of HRB in clathrin-dependent endocytosis., PMID:18819912
The acroplaxome is the docking site of Golgi-derived myosin Va/Rab27a/b- containing proacrosomal vesicles in wild-type and Hrb mutant mouse spermatids., PMID:14724135
hRIP, a cellular cofactor for Rev function, promotes release of HIV RNAs from the perinuclear region., PMID:14701878
Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta., PMID:9405152