Catalog No.
PHF40701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ACTR2 (Met1-Arg394).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Actin-like protein 2, ARP2, Actin-related protein 2, ACTR2
Purification
Purified by antigen affinity column.
Accession
P61160
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Interaction of species A rotavirus VP4 with the cellular proteins vimentin and actin related protein 2 discovered by a proximity interactome assay., PMID:37991368
Nuclear interaction of Arp2/3 complex and BRAFV600E promotes aggressive behavior and vemurafenib resistance of thyroid cancer., PMID:35968344
Influence of external forces on actin-dependent T cell protrusions during immune synapse formation., PMID:33471387
ATG5 is required for B cell polarization and presentation of particulate antigens., PMID:30196744
ox-LDL induces endothelial dysfunction by promoting Arp2/3 complex expression., PMID:27181356
CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity., PMID:23644663
Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal protein related to epileptic seizure., PMID:20934411
MRP-1/CD9 gene transduction regulates the actin cytoskeleton through the downregulation of WAVE2., PMID:16682943
Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility., PMID:16027158
Involvement of Arp2/3 complex in MCP-1-induced chemotaxis., PMID:16004967
Activated cofilin colocalises with Arp2/3 complex in apoptotic blebs during programmed cell death., PMID:15900709
Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement., PMID:15741236
Actin-related protein 2/3 complex is required for actin ring formation., PMID:15040839
RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery., PMID:14742709
Actin-based motility of Burkholderia pseudomallei involves the Arp 2/3 complex, but not N-WASP and Ena/VASP proteins., PMID:12780776
Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP., PMID:12769847
A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton., PMID:12672817
Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16-ARC/ARPC5., PMID:12451597
Syndapins integrate N-WASP in receptor-mediated endocytosis., PMID:12426380
Novel actin-related proteins Arp-T1 and Arp-T2 as components of the cytoskeletal calyx of the mammalian sperm head., PMID:12243744
Arp2/3 complex is required for actin polymerization during platelet shape change., PMID:12036877
Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells., PMID:11706047
Yersinia enterocolitica invasin triggers phagocytosis via beta1 integrins, CDC42Hs and WASp in macrophages., PMID:11580754
CD2AP and p130Cas localize to different F-actin structures in podocytes., PMID:11553524
ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity., PMID:11483954
The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension., PMID:11369208
WIP regulates N-WASP-mediated actin polymerization and filopodium formation., PMID:11331876
Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex., PMID:10995437
The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex., PMID:10861055
Monoclonal antibodies that recognize the type-2 activin receptor, ACTR2., PMID:7927363
Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor., PMID:8307945
For research use only. Not for human or drug use.
