Catalog No.
PHD51801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human USF1 (Glu190-Asn310).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Upstream stimulatory factor 1, bHLHb11, BHLHB11, Major late transcription factor 1, USF, Class B basic helix-loop-helix protein 11, USF1
Purification
Purified by antigen affinity column.
Accession
P22415
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer., PMID:38992029
USF1-mediated ALKBH5 stabilizes FLII mRNA in an m6A-YTHDF2-dependent manner to repress glycolytic activity in prostate adenocarcinoma., PMID:37493109
Upregulation of DNMT1 mediated by HBx suppresses RASSF1A expression independent of DNA methylation., PMID:24247422
Statins modulate transcriptional activity of heme-oxygenase-1 promoter in NIH 3T3 Cells., PMID:22689023
Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest., PMID:19427096
Follicle-stimulating hormone (FSH) transiently blocks FSH receptor transcription by increasing inhibitor of deoxyribonucleic acid binding/differentiation-2 and decreasing upstream stimulatory factor expression in rat Sertoli cells., PMID:19423764
Glucose increases hepatic lipase expression in HepG2 liver cells through upregulation of upstream stimulatory factors 1 and 2., PMID:18758746
[Expression, subcellular localization and nuclear translocation of transcription factor up stream stimulatory factor-1 in odontoblasts]., PMID:18070436
Upstream stimulatory factors regulate the C/EBP alpha gene during differentiation of 3T3-L1 preadipocytes., PMID:17239350
Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: role of USF transcription factors., PMID:17186551
Involvement of upstream stimulatory factor in regulation of the mouse Prnd gene coding for Doppel protein., PMID:16297464
Identification of an E-box motif as a transcriptional repressor element in the proximal promoter region of the GCLC gene in rat lung epithelial L2 cells., PMID:16198230
[Experimental study of E-box, a transcriptional suppressor element in gamma-GCS gene]., PMID:15949339
Down-regulation of the polymeric immunoglobulin receptor in non-small cell lung carcinoma: correlation with dysregulated expression of the transcription factors USF and AP2., PMID:15864740
Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene., PMID:14644095
Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity., PMID:14514691
Interferon-gamma regulation of the human mimecan promoter., PMID:12835654
Interaction of upstream stimulatory factor proteins with an E-box located within the human CYP1A2 5'-flanking gene contributes to basal transcriptional gene activation., PMID:12663044
The Xenopus B2 factor involved in TFIIIA gene regulation is closely related to Sp1 and interacts in a complex with USF., PMID:12609741
Transcription factor USF2 is developmentally regulated in fetal lung and acts together with USF1 to induce SP-A gene expression., PMID:12576297
Orphan receptor chicken ovalbumin upstream promoter transcription factors inhibit steroid factor-1, upstream stimulatory factor, and activator protein-1 activation of ovine follicle-stimulating hormone receptor expression via composite cis-elements., PMID:12021044
Combining chromatin immunoprecipitation and DNA footprinting: a novel method to analyze protein-DNA interactions in vivo., PMID:12000849
The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene., PMID:11861672
Up-regulation of upstream stimulatory factors by protein malnutrition and its possible role in regulation of the IGF-binding protein-1 gene., PMID:11606429
A complex composed of USF1 and USF2 activates the human FcepsilonRI alpha chain expression via a CAGCTG element in the first intron., PMID:11180124
Upstream stimulatory factor is involved in the regulation of the human calcyclin (S100A6) gene., PMID:11118618
Identification of upstream stimulatory factor as an activator of the human dipeptidyl peptidase IV gene in Caco-2 cells., PMID:11111045
Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor., PMID:10947851
Expression of steroidogenic factor 1 in the testis requires an E box and CCAAT box in its promoter proximal region., PMID:10684809
E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer., PMID:10585887
Isolation and initial characterization of the BRCA2 promoter., PMID:10557089
Real-time study of interactions between a composite DNA regulatory region (HIV-1 LTR NRE) and several transcription factors of nuclear extracts., PMID:10527831
B cell-specific activator protein prevents two activator factors from binding to the immunoglobulin J chain promoter until the antigen-driven stages of B cell development., PMID:10336503
Characterization and purification of carbohydrate response element-binding protein of the rat L-type pyruvate kinase gene promoter., PMID:10092507
Cooperative binding of upstream stimulatory factor and hepatic nuclear factor 4 drives the transcription of the human apolipoprotein A-II gene., PMID:9880489
c-Myc target gene specificity is determined by a post-DNAbinding mechanism., PMID:9811896
Multiple promoter elements contribute to activity of the follicle-stimulating hormone receptor (FSHR) gene in testicular Sertoli cells., PMID:9773974
Characterization of the 5'-flanking region of the murine polymeric IgA receptor gene., PMID:9756509
Nuclear translocation of upstream stimulating factor 2 (USF2) in activated mast cells: a possible role in their survival., PMID:9743349
Upstream stimulatory factors mediate estrogen receptor activation of the cathepsin D promoter., PMID:9731700
Identification of upstream stimulatory factor as transcriptional activator of the liver promoter of the glucokinase gene., PMID:9677331
The basic helix-loop-helix, leucine zipper transcription factor, USF (upstream stimulatory factor), is a key regulator of SF-1 (steroidogenic factor-1) gene expression in pituitary gonadotrope and steroidogenic cells., PMID:9605934
Transcriptional regulation of the human nonmuscle myosin II heavy chain-A gene. Identification of three clustered cis-elements in intron-1 which modulate transcription in a cell type- and differentiation state-dependent manner., PMID:9535907
Regulation of cardiac alpha-myosin heavy chain gene transcription by a contractile-responsive E-box binding protein., PMID:9500867
Inhibition of the transcription of CYP1A1 gene by the upstream stimulatory factor 1 in rabbits. Competitive binding of USF1 with AhR.Arnt complex., PMID:9374477
Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter., PMID:9334210
A minimal murine Msx-1 gene promoter. Organization of its cis-regulatory motifs and their role in transcriptional activation in cells in culture and in transgenic mice., PMID:9278425
Upstream stimulatory factor family binds to the herpes simplex virus type 1 latency-associated transcript promoter., PMID:9143295
Transcriptional regulation of the mouse alpha A-crystallin gene: binding of USF to the -7/+5 region., PMID:9055817
Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins., PMID:8995271
For research use only. Not for human or drug use.
