Catalog No.
PHD07101
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human POU2F1 (Ala413-Val671).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Oct-1,OTF-1,NF-A1,Octamer-binding transcription factor 1,Octamer-binding protein 1,POU2F1,OCT1,POU domain,class 2,transcription factor 1,OTF1
Purification
Purified by antigen affinity column.
Accession
P14859
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers., PMID:40442146
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Bob1 maintains T follicular helper cells for long-term humoral immunity., PMID:38360857
Differences in transcriptional changes in psoriasis and psoriatic arthritis skin with immunoglobulin gene enrichment in psoriatic arthritis., PMID:37137278
Analysis of Anti-RNA Polymerase III Antibody-positive Systemic Sclerosis and Altered GPATCH2L and CTNND2 Expression in Scleroderma Renal Crisis., PMID:32173657
Stress-induced release of Oct-1 from the nuclear envelope is mediated by JNK phosphorylation of lamin B1., PMID:28542436
The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma., PMID:28178663
Methylation analysis of histone H4K12ac-associated promoters in sperm of healthy donors and subfertile patients., PMID:25806092
Collaborative interaction of Oct-2 with Oct-1 in transactivation of lactogenic hormones-induced β-casein gene expression in mammary epithelial cells., PMID:24861805
Development of a plasmid display system with an Oct-1 DNA-binding domain suitable for in vitro screening of engineered proteins., PMID:23490644
Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells., PMID:21399967
Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)., PMID:21320718
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines., PMID:20363215
Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1., PMID:18674516
Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels., PMID:18602573
Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line., PMID:16164021
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5., PMID:16025120
Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia., PMID:15672409
Rhinovirus 3C protease precursors 3CD and 3CD' localize to the nuclei of infected cells., PMID:15448360
Analysis of transcription factor OCT.1, OCT.2 and BOB.1 expression using tissue arrays in classical Hodgkin's lymphoma., PMID:15257313
The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination., PMID:15252056
Quantitative high-throughput analysis of transcription factor binding specificities., PMID:14990752
B cell development and immunoglobulin transcription in Oct-1-deficient mice., PMID:14762167
NF-kappa B and Oct-2 synergize to activate the human 3' Igh hs4 enhancer in B cells., PMID:14707079
Analysis of a repressor region in the human neuropeptide Y gene that binds Oct-1 and Pbx-1 in GT1-7 neurons., PMID:12878188
Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements., PMID:12672812
Oct-1 is involved in the transcriptional repression of the gonadotropin-releasing hormone receptor gene., PMID:12446597
Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication., PMID:12393188
Involvement of Oct-1 in transcriptional regulation of beta-casein gene expression in mouse mammary gland., PMID:12151092
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells., PMID:12144930
Bob1 (OCA-B/OBF-1) differential transactivation of the B cell-specific B29 (Ig beta) and mb-1 (Ig alpha) promoters., PMID:11907094
Tissue-specific isoforms of the ubiquitous transcription factor Oct-1., PMID:11683265
HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: evidence for specific promoter-enhancer interactions., PMID:11544313
The POU homeodomain protein Oct-1 binds Cis-regulatory element essential for the human GnRH upstream promoter activity in JEG-3 cells., PMID:11397896
Allele-specific binding of the ubiquitous transcription factor OCT-1 to the functional single nucleotide polymorphism (SNP) sites in the tumor necrosis factor-alpha gene (TNFA) promoter., PMID:11393654
A conserved sequence block in the murine and human T cell receptor Jalpha loci interacts with developmentally regulated nucleoprotein complexes in vitro and associates with GATA-3 and octamer-binding factors in vivo., PMID:11385613
Cellular transcription factors that interact with p6 promoter elements of parvovirus B19., PMID:11369893
Transcriptional regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions., PMID:11126367
An essential octamer motif in the mb-1 (Igalpha) promoter., PMID:11000405
Oct-1 specifically binds the UEF4 site of the human AP1-regulated urokinase enhancer., PMID:10951201
Octamer transcription factor-1 enhances hepatic nuclear factor-1alpha-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter., PMID:10779377
Transcription factors Oct-1 and C/EBPbeta (CCAAT/enhancer-binding protein-beta) are involved in the glutamate/nitric oxide/cyclic-guanosine 5'-monophosphate-mediated repression of mediated repression of gonadotropin-releasing hormone gene expression., PMID:10674395
Binding of octamer factors to a novel 3'-positive regulatory element in the mouse interleukin-5 gene., PMID:10660628
Interaction and functional interference of C/EBPbeta with octamer factors in immunoglobulin gene transcription., PMID:10602039
The activity of the human interleukin-5 conserved lymphokine element 0 is regulated by octamer factors in human cells., PMID:10491186
Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors., PMID:10396620
Functional map of a placenta-specific enhancer of the human leukemia inhibitory factor receptor gene., PMID:9748286
Transcription factor AP1 is involved in basal and okadaic acid-stimulated activity of the human PRL promoter., PMID:9717847
Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter., PMID:9705324
MEF-2 and Oct-1 bind to two homologous promoter sequence elements and participate in the expression of a skeletal muscle-specific gene., PMID:9614136