Catalog No.
PHD95401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CASQ1 (Asn56-Asp396).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Calsequestrin, skeletal muscle isoform, CASQ, Calmitine, CASQ1, Calsequestrin-1
Purification
Purified by antigen affinity column.
Accession
P31415
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves' ophthalmopathy and Hashimoto's thyroiditis., PMID:26445519
Eye findings and immunological markers in probands and their euthyroid relatives from a single family with multiple cases of thyroid autoimmunity., PMID:22742084
[Pathogenesis of thyroid eye disease - does autoimmunity against the TSH receptor explain all cases?]., PMID:22125104
Epitopes, immunoglobulin classes and immunoglobulin G subclasses of calsequestrin antibodies in patients with thyroid eye disease., PMID:20670117
Pathogenesis of thyroid eye disease--does autoimmunity against the TSH receptor explain all cases?, PMID:20464711
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure., PMID:20032264
Can autoimmunity against calsequestrin explain the eye and eyelid muscle inflammation of thyroid eye disease?, PMID:19839885
Egr-1 negatively regulates calsequestrin expression and calcium dynamics in ventricular cells., PMID:19103607