Catalog No.
PHF59201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SNRPN (Thr2-Gly84).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SNRPN, HCERN3, Sm-N, Sm-D, SmN, Sm protein D, Small nuclear ribonucleoprotein-associated protein N, snRNP-N, Sm protein N, SMN, Tissue-specific-splicing protein
Purification
Purified by antigen affinity column.
Accession
P63162
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Epigenetic modifications at DMRs of imprinting genes in sperm of type 2 diabetic men., PMID:35603594
Epstein-Barr Functional Mimicry: Pathogenicity of Oncogenic Latent Membrane Protein-1 in Systemic Lupus Erythematosus and Autoimmunity., PMID:33613527
Pregnancy outcome in systemic lupus erythematosus patients: a monocentric cohort analysis., PMID:33083843
Identification of highly active systemic lupus erythematosus by combined type I interferon and neutrophil gene scores vs classical serologic markers., PMID:32375176
Synergistic enhancement of production of proinflammatory cytokines of human peripheral blood monocytes by anti-Sm and anti-RNP antibodies., PMID:30571738
Anti-RNP/Sm antibodies in patients with systemic lupus erythematosus and its role in thrombosis: a case-control study., PMID:30515663
Nature of T cell epitopes in lupus antigens and HLA-DR determines autoantibody initiation and diversification., PMID:30254034
Antibodies to extractable nuclear antigens (ENAS) in systemic lupus erythematosus patients: correlations with clinical manifestations and disease activity., PMID:29976042
Role of serum autoantibodies in blood brain barrier damages in neuropsychiatric systemic lupus erythematosus., PMID:29846157
Origins and specificity of auto-antibodies in Sm+ SLE patients., PMID:29503043
Anti-SmD1 antibodies are associated with renal disorder, seizures, and pulmonary arterial hypertension in Chinese patients with active SLE., PMID:28790444
Serological biomarkers as risk factors of SLE-associated pulmonary arterial hypertension: a systematic review and meta-analysis., PMID:28409522
What is the clinical significance of anti-Sm antibodies in systemic lupus erythematosus? A comparison with anti-dsDNA antibodies and C3., PMID:28281463
Clinical Images: Arytenoid Chondritis., PMID:28257603
Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach., PMID:28204086
Evaluating Anti-SmD1-amino-acid 83-119 Peptide Reactivity in Children with Systemic Lupus Erythematosus and Other Immunological Diseases., PMID:27900999
Prion-like Aggregation of Mitochondrial Antiviral Signaling Protein in Lupus Patients Is Associated With Increased Levels of Type I Interferon., PMID:27110677
The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing., PMID:27575636
Linear atrophoderma of Moulin: a disease related to immunity or a kind of connective tissue disease?, PMID:27283080
Anti-Sm is associated with the early poor outcome of lupus nephritis., PMID:27126359
Embryos aggregation improves development and imprinting gene expression in mouse parthenogenesis., PMID:26991405
Maintenance of autoantibody production in pristane-induced murine lupus., PMID:26717913
A Central Role for HLA-DR3 in Anti-Smith Antibody Responses and Glomerulonephritis in a Transgenic Mouse Model of Spontaneous Lupus., PMID:26475924
Analysis of immunity index and immunopathogenesis pattern of lupus nephritis patients., PMID:25864759
Serum SmD autoantibody proteomes are clonally restricted and share variable-region peptides., PMID:25577500
Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL., PMID:25564405
The spliceosomal PRP19 complex of trypanosomes., PMID:25524563
Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts., PMID:25466894
Association of cerebrospinal fluid anti-Sm antibodies with acute confusional state in systemic lupus erythematosus., PMID:25273532
Modulation of alternative splicing by expression of small nuclear ribonucleoprotein polypeptide N., PMID:25238490
Low complements and high titre of anti-Sm antibody as predictors of histopathologically proven silent lupus nephritis without abnormal urinalysis in patients with systemic lupus erythematosus., PMID:25183834
A newborn with grouped facial skin lesions and subsequent seizures., PMID:24884686
[Evolution of autoantibodies profile in systemic lupus erythematosus according to age and clinical manifestations]., PMID:24876146
TULUP (TUnisian LUPus): a multicentric study of systemic lupus erythematosus in Tunisia., PMID:24164841
CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development., PMID:24036311
Expression, localization and clinical application of exogenous Smith proteins D1 in gene transfected HEp-2 cells., PMID:23981752
A case of late-onset systemic lupus erythematosus with severe anemia., PMID:23925156
Interferon-α induction and detection of anti-ro, anti-la, anti-sm, and anti-rnp autoantibodies by autoantigen microarray analysis in juvenile dermatomyositis., PMID:23740815
[Lupus pancreatitis: A case series of six patients]., PMID:22884286
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression., PMID:22879910
Non-canonical Cajal bodies form in the nucleus of late stage avian oocytes lacking functional nucleolus., PMID:22382586
Soluble receptor activator of nuclear factor κB ligand/osteoprotegerin ratio is increased in systemic lupus erythematosus patients., PMID:22027240
HLA-DR3 restricted T cell epitope mimicry in induction of autoimmune response to lupus-associated antigen SmD., PMID:21868195
Subset size, activation threshold and distribution of autoreactive MZ and FO B cells do not differ in a sex-specific manner in the NZB/W F1 murine lupus model: an experimental mouse study., PMID:21844114
snRNA-specific role of SMN in trypanosome snRNP biogenesis in vivo., PMID:21282982
Serum and organ-associated anti-hemoglobin humoral autoreactivity: association with anti-Sm responses and inflammation., PMID:21268022
Performance of a multiplex assay compared to enzyme and precipitation methods for anti-ENA testing in systemic lupus and systemic sclerosis., PMID:21184759
[Anti-Sm antibodies]., PMID:20942121
Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus., PMID:20845080
Neonatal lupus erythematosus: a possible role for anti-Sm antibodies., PMID:20133347
For research use only. Not for human or drug use.
