Catalog No.
PHK59701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TFG (Ser8-Gln93).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein TFG, TRK-fused gene protein, TFG
Purification
Purified by antigen affinity column.
Accession
Q92734
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting molecular pathways to control immune checkpoint inhibitor toxicities., PMID:39732529
Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours., PMID:39663448
Biosimilar monoclonal antibodies for cancer treatment in adults., PMID:39607013
Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy., PMID:38656869
Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses., PMID:38623463
Immunogenic epitope scanning in bacteriolytic enzymes Pal and Cpl-1 and engineering Pal to escape antibody responses., PMID:37781366
Design and investigation of targeting agent orientation and density on nanoparticles for enhancing cellular uptake efficiency., PMID:37565424
Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas., PMID:37385724
Germline immunomodulatory expression quantitative trait loci (ieQTLs) associated with immune-related toxicity from checkpoint inhibition., PMID:37301715
Changes in TFG gene expression in bovine leucocytes transformed by Theileria annulata., PMID:36337204
Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer therapies., PMID:35732350
Molecular Characterization of Inflammatory Tumors Facilitates Initiation of Effective Therapy., PMID:34814185
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma., PMID:34518290
TFG binds LC3C to regulate ULK1 localization and autophagosome formation., PMID:33932238
Preeclampsia: Cardiotonic Steroids, Fibrosis, Fli1 and Hint to Carcinogenesis., PMID:33669287
Primary hypothyroidism and autoimmune thyroiditis alter the transcriptional activity of genes regulating neurogenesis in the blood of patients., PMID:33600668
Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and anti-metastatic activities., PMID:32928251
TFG is required for autophagy flux and to prevent endoplasmic reticulum stress in CH12 B lymphoma cells., PMID:32910713
Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy)., PMID:32894202
Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19., PMID:32300051
A case of dual-mechanism immune-related anaemia in a patient with metastatic melanoma treated with nivolumab and ipilimumab., PMID:32169870
Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma., PMID:31703593
Muscle pathology of hereditary motor and sensory neuropathy with proximal dominant involvement with TFG mutation., PMID:31449671
Spatial and temporal immunoreactivity in the rat brain using an affinity purified polyclonal antibody to DNSP-11., PMID:31394198
Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma., PMID:30894212
Rapid Growth and Early Metastasis of Papillary Thyroid Carcinoma in an Adolescent Girl with Graves' Disease., PMID:30092570
Severe hemophagocytic lymphohistiocytosis in a melanoma patient treated with ipilimumab + nivolumab., PMID:30012206
Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration., PMID:29486577
A novel immunosensor based on excessively tilted fiber grating coated with gold nanospheres improves the detection limit of Newcastle disease virus., PMID:28888179
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis., PMID:28356511
Human heart failure biomarker immunosensor based on excessively tilted fiber gratings., PMID:28101401
Label-free immunoassay for porcine circovirus type 2 based on excessively tilted fiber grating modified with staphylococcal protein A., PMID:27518582
Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors., PMID:25612511
TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization., PMID:25586378
Immunohistochemical Localization of an Isoform of TRK-Fused Gene-Like Protein in the Rat Retina., PMID:25221366
Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial., PMID:24852116
Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin-proteasome system., PMID:24613659
Fingolimod reduces recurrence of disease activity after natalizumab withdrawal in multiple sclerosis., PMID:23266894
Transforming growth factor-β neutralizing antibodies inhibit subretinal fibrosis in a mouse model., PMID:22773978
Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem., PMID:22489105
Expression and Localization of TRK-Fused Gene Products in the Rat Brain and Retina., PMID:22489101
New advances in the treatment of gout: review of pegloticase., PMID:21127695
Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells., PMID:19433458
[Effect of nebulized TFG on Th1/Th2 imbalance in mouse model with asthma]., PMID:19007018
Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells., PMID:18941193
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration., PMID:18688035
[Morphological tumor front grading and matrix metalloproteinases type I expression as a prognostic parameter of the presence of lymph node micrometastases in laryngeal carcinoma]., PMID:18552024
Early administration of abciximab bolus in the emergency department improves angiographic outcome after primary PCI as assessed by TIMI frame count: results of the early ReoPro administration in myocardial infarction (ERAMI) trial., PMID:16817177
Serum TGF-beta1 correlates with chronic histopathological lesions in protocol biopsies of kidney allograft recipients., PMID:15848527
Combined assessment of thrombolysis in myocardial infarction flow grade, myocardial perfusion grade, and ST-segment resolution to evaluate epicardial and myocardial reperfusion., PMID:15165915
For research use only. Not for human or drug use.
