Catalog No.
PHK56201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EGLN3 (Met1-Asp239).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PHD3, Hypoxia-inducible factor prolyl hydroxylase 3, Prolyl hydroxylase EGLN3, HPH-3, Prolyl hydroxylase domain-containing protein 3, Egl nine homolog 3, HIF-PH3, HIF-prolyl hydroxylase 3, HPH-1, EGLN3
Purification
Purified by antigen affinity column.
Accession
Q9H6Z9
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Multiple polygenic risk scores can improve the prediction of systemic lupus erythematosus in Taiwan., PMID:38724181
β-CATENIN stabilizes HIF2 through lncRNA and inhibits intravenous immunoglobulin immunotherapy., PMID:37744383
Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma., PMID:35973929
Tumor innervation is triggered by endoplasmic reticulum stress., PMID:34785777
Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions., PMID:26372732
Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27., PMID:26223520
Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile., PMID:25319955
Genetic markers of bevacizumab-induced hypertension., PMID:24558090
Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells., PMID:23400594
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1., PMID:21620138
Autoantibody against hypoxia-inducible factor prolyl hydroxylase-3 is a potential serological marker for renal cell carcinoma., PMID:20676679
Double immunohistochemical staining method for HIF-1alpha and its regulators PHD2 and PHD3 in formalin-fixed paraffin-embedded tissues., PMID:20216402
Identification of an immunogenic CTL epitope of HIFPH3 for immunotherapy of renal cell carcinoma., PMID:18980986
IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells., PMID:18342537
Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues., PMID:16324198
A nonradioactive 96-well plate assay for the detection of hypoxia-inducible factor prolyl hydroxylase activity., PMID:15183764
Angiotensin II's antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20., PMID:12379765
SM-20 is a novel 40-kd protein whose expression in the arterial wall is restricted to smooth muscle., PMID:8606489
For research use only. Not for human or drug use.
