Catalog No.
PHE96801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NKX2-5 (Ser146-Gly206).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NKX2E, CSX, Homeobox protein Nkx-2.5, NKX2.5, NKX2-5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E
Purification
Purified by antigen affinity column.
Accession
P52952
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Circulating GDF11 exacerbates myocardial injury in mice and associates with increased infarct size in humans., PMID:37742057
Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells., PMID:30281646
Isolation, Characterization and Differentiation of Mouse Cardiac Progenitor Cells., PMID:30196409
Characteristics and Cardiomyogenic Potential of Rat Fetal Cardiac Progenitor Cells at Different Developmental Stage., PMID:30603482
Polymer microfiber meshes facilitate cardiac differentiation of c-kit(+) human cardiac stem cells., PMID:27481582
Overexpressing NKx2.5 increases the differentiation of human umbilical cord drived mesenchymal stem cells into cardiomyocyte-like cells., PMID:26898431
Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development., PMID:26822476
Arsenic trioxide alters the differentiation of mouse embryonic stem cell into cardiomyocytes., PMID:26447599
Cardiac tissue inhibitor of matrix metalloprotease 4 dictates cardiomyocyte contractility and differentiation of embryonic stem cells into cardiomyocytes: Road to therapy., PMID:25745981
Adipose-derived stem cell adhesion on laminin-coated microcarriers improves commitment toward the cardiomyogenic lineage., PMID:25098676
Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule., PMID:24958154
Pax3 and Tbx5 specify whether PDGFRα+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells., PMID:24677751
Pregnancy-induced physiological hypertrophy protects against cardiac ischemia-reperfusion injury., PMID:24427343
Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3., PMID:24120474
N-Cadherin is a prospective cell surface marker of human mesenchymal stem cells that have high ability for cardiomyocyte differentiation., PMID:23899519
Identification and biological characterization of chicken embryonic cardiac progenitor cells., PMID:23510478
Second heart field and the development of the outflow tract in human embryonic heart., PMID:23488909
Cardiomyocyte differentiation of perinatally‑derived mesenchymal stem cells., PMID:23467912
Haemogenic endocardium contributes to transient definitive haematopoiesis., PMID:23463007
Heart cells with regenerative potential from pediatric patients with end stage heart failure: a translatable method to enrich and propagate., PMID:22936950
Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells., PMID:22884695
Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5., PMID:21931855
Developmental patterns and characteristics of epicardial cell markers Tbx18 and Wt1 in murine embryonic heart., PMID:21871065
HDAC inhibition promotes cardiogenesis and the survival of embryonic stem cells through proteasome-dependent pathway., PMID:21751234
Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network., PMID:21694703
Over-expression of Nkx2.5 and/or cardiac α-actin inhibit the contraction ability of ADSCs-derived cardiomyocytes., PMID:21691712
Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias., PMID:21399557
Identification and isolation from either adult human bone marrow or G-CSF-mobilized peripheral blood of CD34(+)/CD133(+)/CXCR4(+)/ Lin(-)CD45(-) cells, featuring morphological, molecular, and phenotypic characteristics of very small embryonic-like (VSEL) stem cells., PMID:21238532
Cardiomyocyte differentiation of rat bone marrow multipotent progenitor cells is associated with downregulation of Oct-4 expression., PMID:20486789
Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure., PMID:20065166
Adenovirus-mediated hypoxia-inducible factor 1alpha double-mutant promotes differentiation of bone marrow stem cells to cardiomyocytes., PMID:19603255
BMP-2 and FGF-2 synergistically facilitate adoption of a cardiac phenotype in somatic bone marrow c-kit+/Sca-1+ stem cells., PMID:20443832
Generation of functional murine cardiac myocytes from induced pluripotent stem cells., PMID:18625890
An efficient two-step method to purify very small embryonic-like (VSEL) stem cells from umbilical cord blood (UCB)., PMID:18519244
Common marmoset embryonic stem cell can differentiate into cardiomyocytes., PMID:18331825
Cardiac stem cells in the real world., PMID:18329492
Muscle-derived stem cells isolated as non-adherent population give rise to cardiac, skeletal muscle and neural lineages., PMID:18282570
Involvement of TGF-beta1 signaling in cardiomyocyte differentiation from P19CL6 cells., PMID:18182860
STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction., PMID:17823373
Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats., PMID:17540853
Peroxisome proliferator-activated receptor alpha is involved in cardiomyocyte differentiation of murine embryonic stem cells in vitro., PMID:17467307
Human cord blood CD133+ cells immunoselected by a clinical-grade apparatus differentiate in vitro into endothelial- and cardiomyocyte-like cells., PMID:17302775
VEGF is critical for spontaneous differentiation of stem cells into cardiomyocytes., PMID:17276389
HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage., PMID:17038545
Vascular endothelial growth factor promotes cardiomyocyte differentiation of embryonic stem cells., PMID:16699073
Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5., PMID:15537493
Two dual-color split signal fluorescence in situ hybridization assays to detect t(5;14) involving HOX11L2 or CSX in T-cell acute lymphoblastic leukemia., PMID:15194534
Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes., PMID:12408979
Quaking is essential for blood vessel development., PMID:11892011
GATA-4 and serum response factor regulate transcription of the muscle-specific carnitine palmitoyltransferase I beta in rat heart., PMID:11038368
For research use only. Not for human or drug use.
