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Anti-Human HEXIM1 Polyclonal Antibody

Catalog #:   PHB51101 Specific References (14) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O94992
Overview

Catalog No.

PHB51101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HEXIM1 (Asp258-Asp359).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protein HEXIM1, Cardiac lineage protein 1, HIS1, Menage a quatre protein 1, EDG1, Estrogen down-regulated gene 1 protein, HEXIM1, Hexamethylene bis-acetamide-inducible protein 1, MAQ1, CLP1

Purification

Purified by antigen affinity column.

Accession

O94992

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Various lysates were subjected to SDS PAGE followed by western blot with HEXIM1 antibody (PHB51101) at 1ug/mL .

    Lane 1: K562 cell lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 41 kDa
    Observed MW: 70 kDa
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with HEXIM1 antibody (PHB51101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 26 kDa
    Observed MW: 26 kDa
References

Plasma proteomic profiling reveals KRT19 could be a potential biomarker in patients with anti-MDA5+ dermatomyositis., PMID:37160775

Tat-Based Therapies as an Adjuvant for an HIV-1 Functional Cure., PMID:32276443

Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy., PMID:26734838

BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells., PMID:25989842

Down-regulation of hypoxia-inducible factor-1 alpha and vascular endothelial growth factor by HEXIM1 attenuates myocardial angiogenesis in hypoxic mice., PMID:25301555

Nonproteolytic roles of 19S ATPases in transcription of CIITApIV genes., PMID:24625964

CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90., PMID:23140174

HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening., PMID:22609015

Nuclear organization and dynamics of 7SK RNA in regulating gene expression., PMID:20881057

The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK., PMID:20808803

Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy., PMID:17459355

HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b., PMID:15941832

Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q., PMID:12532422

Identification of a novel cardiac lineage-associated protein(cCLP-1): A candidate regulator of cardiogenesis., PMID:10075853

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human HEXIM1 Polyclonal Antibody [PHB51101]
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