Catalog No.
PHB51101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HEXIM1 (Asp258-Asp359).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein HEXIM1, Cardiac lineage protein 1, HIS1, Menage a quatre protein 1, EDG1, Estrogen down-regulated gene 1 protein, HEXIM1, Hexamethylene bis-acetamide-inducible protein 1, MAQ1, CLP1
Purification
Purified by antigen affinity column.
Accession
O94992
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Plasma proteomic profiling reveals KRT19 could be a potential biomarker in patients with anti-MDA5+ dermatomyositis., PMID:37160775
Tat-Based Therapies as an Adjuvant for an HIV-1 Functional Cure., PMID:32276443
Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy., PMID:26734838
BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells., PMID:25989842
Down-regulation of hypoxia-inducible factor-1 alpha and vascular endothelial growth factor by HEXIM1 attenuates myocardial angiogenesis in hypoxic mice., PMID:25301555
Nonproteolytic roles of 19S ATPases in transcription of CIITApIV genes., PMID:24625964
CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90., PMID:23140174
HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening., PMID:22609015
Nuclear organization and dynamics of 7SK RNA in regulating gene expression., PMID:20881057
The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK., PMID:20808803
Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy., PMID:17459355
HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b., PMID:15941832
Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q., PMID:12532422
Identification of a novel cardiac lineage-associated protein(cCLP-1): A candidate regulator of cardiogenesis., PMID:10075853