Catalog No.
PHK46701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SPAG5 (Met976-Asp1098).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Sperm-associated antigen 5, SPAG5, Astrin, Deepest, MAP126, Mitotic spindle-associated protein p126
Purification
Purified by antigen affinity column.
Accession
Q96R06
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
SPAG5 is a potential therapeutic target affecting proliferation, apoptosis, and invasion of esophageal cancer cells., PMID:39696708
Landscape of tumor-infiltrating T cell repertoire of human cancers., PMID:27240091
OSBP-related protein 8 (ORP8) interacts with Homo sapiens sperm associated antigen 5 (SPAG5) and mediates oxysterol interference of HepG2 cell cycle., PMID:24424245
Low expression of a few genes indicates good prognosis in estrogen receptor positive breast cancer., PMID:19619298
Reduced mitotic activity and increased apoptosis of fetal sertoli cells in rat hypogonadic (hgn/hgn) testes., PMID:17310077
Duplicated insertion mutation in the microtubule-associated protein Spag5 (astrin/MAP126) and defective proliferation of immature Sertoli cells in rat hypogonadic (hgn/hgn) testes., PMID:16816335
Rat Spag5 associates in somatic cells with endoplasmic reticulum and microtubules but in spermatozoa with outer dense fibers., PMID:16211599
Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein., PMID:11724960
Cloning and characterization of hMAP126, a new member of mitotic spindle-associated proteins., PMID:11549262
For research use only. Not for human or drug use.
