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Anti-Human VDAC2 Polyclonal Antibody

Catalog #:   PHE45401 Specific References (31) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P45880
Overview

Catalog No.

PHE45401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human VDAC2 (Gly36-Ala294).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Outer mitochondrial membrane protein porin 2, Voltage-dependent anion-selective channel protein 2, VDAC2, hVDAC2, VDAC-2

Purification

Purified by antigen affinity column.

Accession

P45880

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with VDAC2 antibody (PHE45401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 30 kDa
    Observed MW: 30 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with VDAC2 antibody (PHE45401) at 1 μg/ml.

    Lane 1: K562

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 33 kDa
    Observed MW: 33 kDa
  • Immunohistochemical
    Immunohistochemical analysis of mouse testis tissue stained for VDAC2 with PHE45401.
References

Sulindac prevents increased mitochondrial VDAC1 expression and cell surface mistargeting induced by pathological conditions in retinal cells., PMID:39181068

Quantum Sensing of Free Radical Generation in Mitochondria of Human Keratinocytes during UVB Exposure., PMID:38743437

Quantum Sensing of Free Radical Generation in Mitochondria of Single Heart Muscle Cells during Hypoxia and Reoxygenation., PMID:38235677

Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane., PMID:36979492

Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy., PMID:31443184

Voltage-Dependent Anion Channel Protein 2 (VDAC2) and Receptor of Activated Protein C Kinase 1 (RACK1) Act as Functional Receptors for Lymphocystis Disease Virus Infection., PMID:30918079

Autoantibody Biomarker Discovery in Primary Open Angle Glaucoma Using Serological Proteome Analysis (SERPA)., PMID:30899261

Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm)., PMID:25680958

Moonlighting proteins in sperm-egg interactions., PMID:25399599

GHSC70 is involved in the cellular entry of nervous necrosis virus., PMID:25320288

Altered dopamine homeostasis differentially affects mitochondrial voltage-dependent anion channels turnover., PMID:24998333

Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique., PMID:24865465

Sperm activation by heat shock protein 70 supports the migration of sperm released from sperm storage tubules in Japanese quail (Coturnix japonica)., PMID:24194572

Differential S-nitrosylation of proteins in Alzheimer's disease., PMID:24157928

Certain Strongylocentrotus purpuratus sperm mitochondrial proteins co-purify with low density detergent-insoluble membranes and are PKA or PKC-substrates possibly involved in sperm motility regulation., PMID:23928041

Identification of sperm head proteins involved in zona pellucida binding., PMID:23355646

The use of anti-VDAC2 antibody for the combined assessment of human sperm acrosome integrity and ionophore A23187-induced acrosome reaction., PMID:21347391

[Research of immunogenic membrane antigens of pancreatic cancer]., PMID:19957813

The VDAC2-BAK rheostat controls thymocyte survival., PMID:19706873

Voltage-dependent anion channels 1 and 2 are expressed in porcine oocytes., PMID:19630752

The proteome of the presynaptic active zone: from docked synaptic vesicles to adhesion molecules and maxi-channels., PMID:19187093

Molecular and functional characterization of VDAC2 purified from mammal spermatozoa., PMID:18976238

The voltage dependent anion selective channel family in Drosophila melanogaster., PMID:19192627

Localisation and function of voltage-dependent anion channels (VDAC) in bovine spermatozoa., PMID:17647012

[Immuno-proteomic screening of human pancreatic cancer associated membrane antigens for early diagnosis]., PMID:17403287

VDAC1, having a shorter N-terminus than VDAC2 but showing the same migration in an SDS-polyacrylamide gel, is the predominant form expressed in mitochondria of various tissues., PMID:17137335

Identification of evolutionary conserved mouse sperm surface antigens by human antisperm antibodies (ASA) from infertile patients., PMID:16635206

Proteomic approach to the identification of voltage-dependent anion channel protein isoforms in guinea pig brain synaptosomes., PMID:15188400

Voltage-dependent anion-selective channels VDAC2 and VDAC3 are abundant proteins in bovine outer dense fibers, a cytoskeletal component of the sperm flagellum., PMID:14739283

Mitochondrial voltage-dependent anion channel is involved in dopamine-induced apoptosis., PMID:12124435

Voltage-dependent anion channel proteins in synaptosomes of the torpedo electric organ: immunolocalization, purification, and characterization., PMID:9932652

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human VDAC2 Polyclonal Antibody [PHE45401]
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