Catalog No.
PHK44301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ING4 (Met1-Lys127).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ING4, Inhibitor of growth protein 4, p29ING4
Purification
Purified by antigen affinity column.
Accession
Q9UNL4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Tissue-specific localization of the ING4 targeting subunit of the HBO1 histone acetyltransferase in the cytoplasm and nucleus of secretory cells., PMID:40402282
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy., PMID:37870169
Autoantibodies against P29ING4 are associated with complex regional pain syndrome., PMID:32008173
A 22q11.2 amplification in the region encoding microRNA-650 correlates with the epithelial to mesenchymal transition in breast cancer primary cultures of Mexican patients., PMID:28101578
Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis., PMID:27752292
Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer., PMID:27349517
ING3 protein expression profiling in normal human tissues suggest its role in cellular growth and self-renewal., PMID:25819753
Inhibitor of growth 4 induces NFκB/p65 ubiquitin-dependent degradation., PMID:23624912
Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer., PMID:23056468
A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis., PMID:20501848
Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility., PMID:16973615
Nuclear localization signal of ING4 plays a key role in its binding to p53., PMID:15882981