Catalog No.
PHG91701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MTF1 (Ser152-Lys227).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Metal regulatory transcription factor 1, MTF1, Transcription factor MTF-1, MRE-binding transcription factor
Purification
Purified by antigen affinity column.
Accession
Q14872
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies., PMID:34140538
PfKsgA1 functions as a transcription initiation factor and interacts with the N-terminal region of the mitochondrial RNA polymerase of Plasmodium falciparum., PMID:32896572
A plasmid containing the human metallothionein II gene can function as an antibody-assisted electrophoretic biosensor for heavy metals., PMID:25594566
Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription., PMID:20599947
STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells., PMID:20133611
The metal-responsive transcription factor-1 protein is elevated in human tumors., PMID:20087061
Investigation of sensitive biomarkers to determine cadmium inducing hepato- and nephro-toxicity in cattle by immunofluorescence method., PMID:19891382
Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions., PMID:18230604
PPARalpha and AP-2alpha regulate bombesin receptor subtype 3 expression in ozone-stressed bronchial epithelial cells., PMID:17355223
Superinduction of metallothionein I by inhibition of protein synthesis: role of a labile repressor in MTF-1 mediated gene transcription., PMID:16615093
Cross talk of heat shock and heavy metal regulatory pathways., PMID:16460681
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure., PMID:12417732
Nucleo-cytoplasmic trafficking of metal-regulatory transcription factor 1 is regulated by diverse stress signals., PMID:11306562
Negative regulatory role of Sp1 in metal responsive element-mediated transcriptional activation., PMID:11279094
Characterization of the mouse metal-regulatory-element-binding proteins, metal element protein-1 and metal regulatory transcription factor-1., PMID:11171056
Zinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1., PMID:10734081
Expression studies and promoter analysis of the nuclear gene for mitochondrial transcription factor 1 (MTF1) in yeast., PMID:10447593
Azf1p is a nuclear-localized zinc-finger protein that is preferentially expressed under non-fermentative growth conditions in Saccharomyces cerevisiae., PMID:9799362
Interactions of the zinc-regulated factor (ZiRF1) with the mouse metallothionein Ia promoter., PMID:9173905
A protein which binds preferentially to single-stranded core sequence of autonomously replicating sequence is essential for respiratory function in mitochondrial of Saccharomyces cerevisiae., PMID:8195160
Characterization of functionally important regions of tissue factor by using monoclonal antibodies., PMID:8113222
A point mutation in the core subunit gene of yeast mitochondrial RNA polymerase is suppressed by a high level of specificity factor MTF1., PMID:8384295
For research use only. Not for human or drug use.
