Catalog No.
PHD54901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LHCGR (Arg43-Phe265).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LHR, LH/CG-R, Lutropin-choriogonadotropic hormone receptor, LCGR, Luteinizing hormone receptor, LGR2, LHCGR, LSH-R, LHRHR
Purification
Purified by antigen affinity column.
Accession
P22888
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis., PMID:38621656
Acute hypoxia induced dysregulation of clock-controlled ovary functions., PMID:36620217
Hormone- and antibody-mediated activation of the thyrotropin receptor., PMID:35940204
Effects of active immunization against a 13-amino acid receptor-binding epitope of FSHβ on fertility regulation in female mice., PMID:35772190
Autoimmunity to the Follicle-Stimulating Hormone Receptor (FSHR) and Luteinizing Hormone Receptor (LHR) in Polycystic Ovarian Syndrome., PMID:34948471
Possible Relevance of Soluble Luteinizing Hormone Receptor during Development and Adulthood in Boys and Men., PMID:33809538
Cisatracurium stimulates testosterone synthesis in rat and mouse Leydig cells via nicotinic acetylcholine receptor., PMID:33111502
Neurotrophin-3 stimulates stem Leydig cell proliferation during regeneration in rats., PMID:33090725
Immunohistochemical demonstration of LH/CG receptors in non-neoplastic human adrenal cortex and adrenocortical tumors., PMID:30924919
Influence of VEGFR and LHCGR on endometrial adenocarcinoma., PMID:27625708
Severe gastrointestinal dysmotility developed after treatment with gonadotropin-releasing hormone analogs., PMID:25592315
The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis., PMID:23391632
Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down's syndrome, preterm delivery and preeclampsia., PMID:23245345
Glycodelin A is a prognostic marker to predict poor outcome in advanced stage ovarian cancer patients., PMID:23036050
Expression of LH receptor in nonpregnant mouse endometrium: LH induction of 3β-HSD and de novo synthesis of progesterone., PMID:22875961
Follicle-stimulating hormone and luteinizing hormone mediate the androgenic pathway in Leydig cells of an evolutionary advanced teleost., PMID:22649073
Decidualization regulates the expression of the endometrial chorionic gonadotropin receptor in the primate., PMID:16837644
A link between high serum levels of human chorionic gonadotrophin and chorionic expression of its mature functional receptor (LHCGR) in Down's syndrome pregnancies., PMID:15969756
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors., PMID:11847099
Characterization of thyroid-stimulating blocking antibodies that appeared during transient hypothyroidism after radioactive iodine therapy., PMID:11081257
Detection of functionally different types of pathological autoantibodies against thyrotropin receptor in Graves' patients sera by luminescent immunoprecipitation analysis., PMID:10826518
Selective binding of thyrotropin receptor autoantibodies to recombinant extracellular domain of thyrotropin/lutropin-chorionic gonadotropin receptor chimeric proteins., PMID:10524566
Epitope heterogeneity of thyrotropin receptor-blocking antibodies in Graves' patients as detected with wild-type versus chimeric thyrotropin receptors., PMID:10411114
Two Graves' disease patients who spontaneously developed hypothyroidism after antithyroid drug treatment: characteristics of epitopes for thyrotropin receptor antibodies., PMID:10319947
Coexpression of gonadotropic hormones and their corresponding FSH- and LH/CG-receptors in the human prostate., PMID:9582090
The formation of thyrotropin receptor (TSHR) antibodies in a Graves' animal model requires the N-terminal segment of the TSHR extracellular domain., PMID:9528975
Epitopes for thyroid stimulating and blocking autoantibodies on the extracellular domain of the human thyrotropin receptor., PMID:9459630
Immunization of male rabbits with sheep luteal receptor to LH results in production of antibodies exhibiting hormone-agonistic and -antagonistic activities., PMID:8882162
High affinity binding of thyrotropin (TSH) and thyroid-stimulating autoantibody for the TSH receptor extracellular domain., PMID:7919997
Thyrotropin stimulation of the lutropin/choriogonadotropin receptor: different sites mediate agonist activity and high affinity binding., PMID:7711510
For research use only. Not for human or drug use.
