Anti-Human IFIT1 Polyclonal Antibody

Catalog No.

PHC44101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IFIT1 (Met1-Pro478).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

IFI-56K, G10P1, Interferon-induced protein with tetratricopeptide repeats 1, IFIT-1, IFNAI1, IFIT1, ISG56, IFI56, Interferon-induced 56 kDa protein, P56

Purification

Purified by antigen affinity column.

Accession

P09914

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling., PMID:40260261

TLR3 signaling-induced interferon-stimulated gene 56 plays a role in the pathogenesis of rheumatoid arthritis., PMID:38881847

Profiling of Early Immune Responses to Vaccination Using THP-1-Derived Dendritic Cells., PMID:38791547

Differentiating central nervous system demyelinating disorders: The role of clinical, laboratory, imaging characteristics and peripheral blood type I interferon activity., PMID:36034800

mRNA-1273 vaccination protects against SARS-CoV-2-elicited lung inflammation in nonhuman primates., PMID:35653196

High Systemic Type I Interferon Activity Is Associated With Active Class III/IV Lupus Nephritis., PMID:34782453

Serum interferon-α2 measured by single-molecule array associates with systemic disease manifestations in Sjögren's syndrome., PMID:34505866

DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome., PMID:34335613

Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE., PMID:34079550

Investigation of type I interferon responses in ANCA-associated vasculitis., PMID:33859290

Proteomic Analysis of ISGylation in Immortalized Porcine Alveolar Macrophage Cell Lines Induced by Type I Interferon., PMID:33671165

Asymptomatic Infection of Marburg Virus Reservoir Bats Is Explained by a Strategy of Immunoprotective Disease Tolerance., PMID:33157026

IFN-γ Mediates the Development of Systemic Lupus Erythematosus., PMID:33123584

Association Between DNA Damage Response, Fibrosis and Type I Interferon Signature in Systemic Sclerosis., PMID:33123169

Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies., PMID:32252809

Signature of genome wide gene expression in classical swine fever virus infected macrophages and PBMCs of indigenous vis-a-vis crossbred pigs., PMID:31935504

Proteome Analysis Reveals Distinct Mitochondrial Functions Linked to Interferon Response Patterns in Activated CD4+ and CD8+ T Cells., PMID:31354474

Type I Interferon Signature in Primary Antiphospholipid Syndrome: Clinical and Laboratory Associations., PMID:30930907

Circulating plasmablasts contribute to antiphospholipid antibody production, associated with type I interferon upregulation., PMID:30864219

The regulation of interferon type I pathway-related genes RSAD2 and ETV7 specifically indicates antibody-mediated rejection after kidney transplantation., PMID:30341925

Identification of New Potential Therapies for Colitis Amelioration Using an Appendicitis-Appendectomy Model., PMID:30329049

Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAI., PMID:30301579

Human Cervical Epithelial Cells Release Antiviral Factors and Inhibit HIV Replication in Macrophages., PMID:30032138

Prediction of response to remission induction therapy by gene expression profiling of peripheral blood in Japanese patients with microscopic polyangiitis., PMID:28569178

Type I interferon signature may influence the effect of belimumab on immunoglobulin levels, including rheumatoid factor in Sjögren's syndrome., PMID:28281461

Integrative Analysis of Immunological Data to Explore Chronic Immune T-Cell Activation in Successfully Treated HIV Patients., PMID:28046052

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study., PMID:27823966

Soybean-derived Bowman-Birk Inhibitor (BBI) Inhibits HIV Replication in Macrophages., PMID:27734899

Vulnerability of atherosclerotic plaques is associated with type I interferon in a murine model of lupus and atherosclerosis., PMID:26600548

Lack of Interferon and Proinflammatory Cyto/chemokines in Serologically Active Clinically Quiescent Systemic Lupus Erythematosus., PMID:26568589

Dengue Virus Infection of Primary Endothelial Cells Induces Innate Immune Responses, Changes in Endothelial Cells Function and Is Restricted by Interferon-Stimulated Responses., PMID:25902155

Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus., PMID:25777546

Increased IFNα activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive deficits., PMID:23141748

Chronic hepatitis E virus infection is specifically associated with an interferon-related transcriptional program., PMID:23072754

Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus., PMID:22307521

Search for specific biomarkers of IFNβ bioactivity in patients with multiple sclerosis., PMID:21886806

Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA., PMID:21690403

The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses., PMID:20519382

Human plasmacytoid dendritic cell accumulation amplifies their type 1 interferon production., PMID:20346735

Effect of neutralizing antibodies on biomarker responses to interferon beta: the INSIGHT study., PMID:19884577

Lack of association between the interferon-alpha signature and longitudinal changes in disease activity in systemic lupus erythematosus., PMID:18772188

Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies., PMID:16736505

Disease-independent skin recruitment and activation of plasmacytoid predendritic cells following imiquimod treatment., PMID:16077073

Interferon-alpha/beta receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006., PMID:12887736

Induction of proteins in interferon-alpha- and interferon-gamma-treated polymorphonuclear leukocytes., PMID:2496191

Production of a monoclonal antibody directed against an interferon-induced 56,000-dalton protein and its use in the study of this protein., PMID:2452894

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