Anti-Human UHRF1 Polyclonal Antibody

Catalog No.

PHK42701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human UHRF1 (Leu134-Asp366).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Nuclear zinc finger protein Np95, RING-type E3 ubiquitin transferase UHRF1, RING finger protein 106, Transcription factor ICBP90, E3 ubiquitin-protein ligase UHRF1, Ubiquitin-like PHD and RING finger domain-containing protein 1, NP95, HuNp95, Nuclear protein 95, RNF106, ICBP90, hNp95, UHRF1, Inverted CCAAT box-binding protein of 90 kDa, hUHRF1, Ubiquitin-like-containing PHD and RING finger domains protein 1

Purification

Purified by antigen affinity column.

Accession

Q96T88

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Potentiating anti-tumor immunity by re-engaging immune synapse molecules., PMID:39999838

Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation., PMID:35951156

Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression., PMID:35664070

ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the MIF Immune Susceptibility Locus., PMID:33844457

PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells., PMID:30012171

Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection., PMID:29618490

UHRF1 is an Independent Prognostic Factor and a Potential Therapeutic Target of Esophageal Squamous Cell Carcinoma., PMID:29187878

In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells., PMID:27979589

E2F8 as a Novel Therapeutic Target for Lung Cancer., PMID:26089541

A modular open platform for systematic functional studies under physiological conditions., PMID:26007658

CD47 activation-induced UHRF1 over-expression is associated with silencing of tumor suppressor gene p16INK4A in glioblastoma cells., PMID:25550546

Epigenetic dysregulation in salivary glands from patients with primary Sjögren's syndrome may be ascribed to infiltrating B cells., PMID:23478041

Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice., PMID:23241950

M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability., PMID:22411829

UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis., PMID:22072796

Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma., PMID:16285947

Cell cycle and/or proliferation markers: what is the best method to discriminate cervical high-grade lesions?, PMID:16226110

Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation., PMID:9880673

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